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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL358289
Molecular formula	C26H38F2N2O2
IUPAC name	(2R)-N-[1-(cycloheptylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Molecular weight	448.599
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.7
Synonyms	SCHEMBL7479389 BDBM50095690 N-(1-Cycloheptylmethyl-piperidin-4-yl)-2-(3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Inchi Key	ANXXZECPSLPAFT-GJZUVCINSA-N
Inchi ID	InChI=1S/C26H38F2N2O2/c27-25(28)15-12-22(18-25)26(32,21-10-6-3-7-11-21)24(31)29-23-13-16-30(17-14-23)19-20-8-4-1-2-5-9-20/h3,6-7,10-11,20,22-23,32H,1-2,4-5,8-9,12-19H2,(H,29,31)/t22-,26+/m1/s1
PubChem CID	10671167
ChEMBL	CHEMBL358289
IUPHAR	N/A
BindingDB	50095690
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10003	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
10002	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
10001	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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