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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL275421
Molecular formula	C22H23N5O
IUPAC name	4-(cyclohexylamino)-2-(3-methylphenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Molecular weight	373.46
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.3
Synonyms	4-Cyclohexylamino-2-m-tolyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one 2-(3-Methylphenyl)-4-(cyclohexylamino)[1,2,4]triazolo[4,3-a]quinoxaline-1(2H)-one 4-(cyclohexylamino)-2-m-tolyl-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one BDBM50086130
Inchi Key	AMXKVGAJMUQALJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23N5O/c1-15-8-7-11-17(14-15)27-22(28)26-19-13-6-5-12-18(19)24-20(21(26)25-27)23-16-9-3-2-4-10-16/h5-8,11-14,16H,2-4,9-10H2,1H3,(H,23,24)
PubChem CID	10667072
ChEMBL	CHEMBL275421
IUPHAR	N/A
BindingDB	50086130
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9336	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
9338	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
9337	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
9339	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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