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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL307554
Molecular formula	C21H22F2N2O2
IUPAC name	(2R)-2-[(1R)-3,3-difluorocyclopentyl]-N-(2,3-dihydro-1H-isoindol-5-yl)-2-hydroxy-2-phenylacetamide
Molecular weight	372.416
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.7
Synonyms	BDBM50129386 (R)-2-((R)-3,3-Difluoro-cyclopentyl)-N-(2,3-dihydro-1H-isoindol-5-yl)-2-hydroxy-2-phenyl-acetamide
Inchi Key	AMOUHXSQTRSDEO-UTKZUKDTSA-N
Inchi ID	InChI=1S/C21H22F2N2O2/c22-20(23)9-8-17(11-20)21(27,16-4-2-1-3-5-16)19(26)25-18-7-6-14-12-24-13-15(14)10-18/h1-7,10,17,24,27H,8-9,11-13H2,(H,25,26)/t17-,21+/m1/s1
PubChem CID	44309108
ChEMBL	CHEMBL307554
IUPHAR	N/A
BindingDB	50129386
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9107	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
9108	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
9106	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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