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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1223747
Molecular formula	C24H27F3N4
IUPAC name	N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]quinolin-2-amine
Molecular weight	428.503
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.7
Synonyms	SCHEMBL4925478 BDBM50325745 N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)quinolin-2-amine
Inchi Key	AMDRAFDQLSKJMW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27F3N4/c25-24(26,27)20-7-5-8-21(18-20)31-16-14-30(15-17-31)13-4-3-12-28-23-11-10-19-6-1-2-9-22(19)29-23/h1-2,5-11,18H,3-4,12-17H2,(H,28,29)
PubChem CID	11590801
ChEMBL	CHEMBL1223747
IUPHAR	N/A
BindingDB	50325745
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8785	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
8784	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
8786	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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