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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL179837
Molecular formula	C35H37ClN4O4S
IUPAC name	N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-[cyclopropylmethyl(methylsulfonyl)amino]phenyl]piperazin-1-yl]-1-oxopropan-2-yl]naphthalene-2-carboxamide
Molecular weight	645.215
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50162716 Naphthalene-2-carboxylic acid ((R)-1-(4-chloro-benzyl)-2-{4-[2-(cyclopropylmethyl-methanesulfonyl-amino)-phenyl]-piperazin-1-yl}-2-oxo-ethyl)-amide
Inchi Key	AMAVLJGPQBNVJH-WJOKGBTCSA-N
Inchi ID	InChI=1S/C35H37ClN4O4S/c1-45(43,44)40(24-26-10-11-26)33-9-5-4-8-32(33)38-18-20-39(21-19-38)35(42)31(22-25-12-16-30(36)17-13-25)37-34(41)29-15-14-27-6-2-3-7-28(27)23-29/h2-9,12-17,23,26,31H,10-11,18-22,24H2,1H3,(H,37,41)/t31-/m1/s1
PubChem CID	44390422
ChEMBL	CHEMBL179837
IUPHAR	N/A
BindingDB	50162716
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8708	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332

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