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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL607689
Molecular formula	C20H22FN3
IUPAC name	2-[[4-(2-fluorophenyl)piperidin-1-yl]methyl]-1-methylbenzimidazole
Molecular weight	323.415
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.6
Synonyms	AMADNKXMEDYTCS-UHFFFAOYSA-N 2-((4-(2-fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole BDBM50343299 (4-(2-fluorophenyl)piperidin-1-ylmethyl)-1-methyl-1H-benzo[d]imidazole 2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole
Inchi Key	AMADNKXMEDYTCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22FN3/c1-23-19-9-5-4-8-18(19)22-20(23)14-24-12-10-15(11-13-24)16-6-2-3-7-17(16)21/h2-9,15H,10-14H2,1H3
PubChem CID	24815439
ChEMBL	CHEMBL607689
IUPHAR	N/A
BindingDB	50343299
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8691	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
8696	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
8697	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
8693	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
8692	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
8695	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
8694	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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