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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1783963
Molecular formula	C20H22FN3
IUPAC name	8-fluoro-2-methyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
Molecular weight	323.415
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.2
Synonyms	8-fluoro-2-methyl-5-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole SCHEMBL4132807 AKOS021644526 8-fluoro-2-methyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole ZINC71294959 BDBM50346052 MolPort-021-806-304 [ Show all ]
Inchi Key	ALOWJQCLRWGVOV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22FN3/c1-14-3-4-15(12-22-14)7-10-24-19-6-5-16(21)11-17(19)18-13-23(2)9-8-20(18)24/h3-6,11-12H,7-10,13H2,1-2H3
PubChem CID	54585846
ChEMBL	CHEMBL1783963
IUPHAR	N/A
BindingDB	50346052
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8470	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
8469	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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