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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000757136
Molecular formula	C17H10ClF3N2O2
IUPAC name	(5-chloroquinolin-8-yl) N-[3-(trifluoromethyl)phenyl]carbamate
Molecular weight	366.724
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.8
Synonyms	NSC-377852 5-chloroquinolin-8-yl [3-(trifluoromethyl)phenyl]carbamate ZINC1590480 AKOS024431677 MCULE-1143231627 (5-chloroquinolin-8-yl) N-[3-(trifluoromethyl)phenyl]carbamate NSC377852 AC1L7VN6 5-chloro-8-quinolinyl 3-(trifluoromethyl)phenylcarbamate SMR000529013 AC1Q4JKY CHEMBL1466186 [ Show all ]
Inchi Key	AJQUXBOOWNSFII-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H10ClF3N2O2/c18-13-6-7-14(15-12(13)5-2-8-22-15)25-16(24)23-11-4-1-3-10(9-11)17(19,20)21/h1-9H,(H,23,24)
PubChem CID	342201
ChEMBL	CHEMBL1466186
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7150	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
7151	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
7152	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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