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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Naloxonazine
Molecular formula	C38H42N4O6
IUPAC name	(4R,4aS,7E,7aR,12bS)-7-[(E)-[(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene]hydrazinylidene]-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Molecular weight	650.776
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	4.0
Synonyms	1-(1-(3-Isothiocyanato)phenyl)cyclohexylpiperidine GTPL1677 NSC 612113, Bis-[5-\|A-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-ylidene] hydrazine dihydrochloride AB01275526-01 Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, ((5alpha)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene)hydrazone, (5alpha)- CHEMBL1618305 NIH-10894 HMS2090F22 NSC-612113 BDBM50135225 (1S,5R,13R,14Z,17S)-14-{2-[(1S,5R,13R,14Z,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18)-trien-14-ylidene]hydrazin-1-ylidene}-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{ D0G1IF NSC 612113 82824-01-9 LS-183744 SCHEMBL264672 NIH 10894 [ Show all ]
Inchi Key	AJPSBXJNFJCCBI-YOHUGVJRSA-N
Inchi ID	InChI=1S/C38H42N4O6/c1-3-15-41-17-13-35-29-21-5-7-25(43)31(29)47-33(35)23(9-11-37(35,45)27(41)19-21)39-40-24-10-12-38(46)28-20-22-6-8-26(44)32-30(22)36(38,34(24)48-32)14-18-42(28)16-4-2/h3-8,27-28,33-34,43-46H,1-2,9-20H2/b39-23+,40-24+/t27-,28-,33+,34+,35+,36+,37-,38-/m1/s1
PubChem CID	9576413
ChEMBL	CHEMBL1618305
IUPHAR	N/A
BindingDB	50135225
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7111	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
7112	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
7113	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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