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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000073240
Molecular formula	C13H13N3O2S
IUPAC name	5-(oxolan-2-ylmethylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile
Molecular weight	275.326
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.0
Synonyms	CHEBI:116357 5-[(tetrahydrofuran-2-ylmethyl)amino]-2-(thiophen-2-yl)-1,3-oxazole-4-carbonitrile AC1MGUYQ cid_2941904 STK896189 AKOS016054522 MLS000062477 5-(tetrahydrofurfurylamino)-2-(2-thienyl)oxazole-4-carbonitrile 5-[(tetrahydrofuran-2-ylmethyl)amino]-2-thien-2-yl-1,3-oxazole-4-carbonitrile SR-01000264807 AF-399/41535426 HMS2490O04 5-(2-oxolanylmethylamino)-2-thiophen-2-yl-4-oxazolecarbonitrile BDBM49080 MolPort-000-181-544 5-[(tetrahydro-2-furanylmethyl)amino]-2-(2-thienyl)-1,3-oxazole-4-carbonitrile 613650-09-2 CHEMBL1414425 SR-01000264807-1 AKOS002686018 MCULE-7663084436 5-(oxolan-2-ylmethylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile [ Show all ]
Inchi Key	AIPQAXWNBFJZCQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H13N3O2S/c14-7-10-12(15-8-9-3-1-5-17-9)18-13(16-10)11-4-2-6-19-11/h2,4,6,9,15H,1,3,5,8H2
PubChem CID	2941904
ChEMBL	CHEMBL1414425
IUPHAR	N/A
BindingDB	49080
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6434	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
6433	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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