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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL385779
Molecular formula	C34H48N6O5
IUPAC name	(2S)-2-amino-N-[4-[5-[3-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propyl]-3-methyl-6-oxo-1H-pyrazin-2-yl]butyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Molecular weight	620.795
Hydrogen bond acceptor	8
Hydrogen bond donor	7
XlogP	2.5
Synonyms	6-[4''-(H-Dmt)-aminobutyl]-3-[3''-(H-Dmt)-aminopropyl]-5-methyl-2(1H)-pyrazinone BDBM50194488 N-[3-[3-Oxo-5-[4-[(2,6-dimethyl-L-tyrosyl)amino]butyl]-6-methyl-3,4-dihydropyrazine-2-yl]propyl]-2,6-dimethyl-L-tyrosinamide
Inchi Key	AIOLFDZVYRFPMH-VMPREFPWSA-N
Inchi ID	InChI=1S/C34H48N6O5/c1-19-13-24(41)14-20(2)26(19)17-28(35)32(43)37-11-7-6-9-30-23(5)39-31(34(45)40-30)10-8-12-38-33(44)29(36)18-27-21(3)15-25(42)16-22(27)4/h13-16,28-29,41-42H,6-12,17-18,35-36H2,1-5H3,(H,37,43)(H,38,44)(H,40,45)/t28-,29-/m0/s1
PubChem CID	44419723
ChEMBL	CHEMBL385779
IUPHAR	N/A
BindingDB	50194488
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6395	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
6398	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
6396	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
6397	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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