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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775177
Molecular formula	C22H28N6O5S
IUPAC name	2-(dimethylamino)ethyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	488.563
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	1.9
Synonyms	142903-EP2292620A2 142903-EP2287165A2 2-(dimethylamino)ethyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate BDBM50343440 142903-EP2287166A2 SCHEMBL389635 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid 2-dimethylamino-ethyl ester [ Show all ]
Inchi Key	AIFHIHRKLSGBNE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N6O5S/c1-26(2)12-13-32-22(29)27-10-8-17(9-11-27)33-21-19-14-25-28(20(19)23-15-24-21)16-4-6-18(7-5-16)34(3,30)31/h4-7,14-15,17H,8-13H2,1-3H3
PubChem CID	21897819
ChEMBL	CHEMBL1775177
IUPHAR	N/A
BindingDB	50343440
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6163	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
6164	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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