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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	141872-46-0
Molecular formula	C23H23N7O2
IUPAC name	4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyrimidine-5-carboxylic acid
Molecular weight	429.484
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.8
Synonyms	ZINC1533713 4-(butyl{[2'-(2h-tetrazol-5-yl)biphenyl-4-yl]methyl}amino)pyrimidine-5-carboxylic acid 5-Pyrimidinecarboxylicacid, 4-[butyl[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]amino]- ACMC-20cd64 CTK8G9360 4-[Butyl([2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl)amino]-5pyrimidinecarboxylic acid A-81282 C-35576 KB-188739 4-{Butyl-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-pyrimidine-5-carboxylic acid;5Hydro chloride AC1L4U4U CHEMBL333534 Oprea1_016094 4-(N-n-Butyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)pyrimidine-5-carboxylic acid AKOS027380884 DTXSID70161839 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyrimidine-5-carboxylic acid Abbott 81282 CC-17571 L006791 SCHEMBL7939345 4-(((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)(butyl)amino)pyrimidine-5-carboxylic acid 5-Pyrimidinecarboxylic acid, 4-(butyl((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)amino)- AC1Q5UC5 CTK0I0417 4-[butyl([2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl)amino]-5-pyrimidinecarboxylic acid A 81282 BDBM50003155 FT-0643333 4-{Butyl-[2''''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-pyrimidine-5-carboxylic acid Abbott-81282 MolPort-039-032-861 [ Show all ]
Inchi Key	AHZXSVWCNDLJER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23N7O2/c1-2-3-12-30(22-20(23(31)32)13-24-15-25-22)14-16-8-10-17(11-9-16)18-6-4-5-7-19(18)21-26-28-29-27-21/h4-11,13,15H,2-3,12,14H2,1H3,(H,31,32)(H,26,27,28,29)
PubChem CID	192314
ChEMBL	CHEMBL333534
IUPHAR	N/A
BindingDB	50003155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6030	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
6031	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359
6032	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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