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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL209380
Molecular formula	C27H33FN2O
IUPAC name	4-(4-fluorophenyl)-8-[1-(3-methylphenyl)cyclohexyl]-2,8-diazaspiro[4.5]decan-1-one
Molecular weight	420.572
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50188845 rac-4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one 4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one SCHEMBL5562071
Inchi Key	AHHHFIOUWFYJQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H33FN2O/c1-20-6-5-7-22(18-20)27(12-3-2-4-13-27)30-16-14-26(15-17-30)24(19-29-25(26)31)21-8-10-23(28)11-9-21/h5-11,18,24H,2-4,12-17,19H2,1H3,(H,29,31)
PubChem CID	11464294
ChEMBL	CHEMBL209380
IUPHAR	N/A
BindingDB	50188845
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5541	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
5540	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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