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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3898811
Molecular formula	C18H22FN3O3
IUPAC name	(2S,4S)-1-[5-cyclopropyl-6-(cyclopropylmethoxy)pyridine-2-carbonyl]-4-fluoropyrrolidine-2-carboxamide
Molecular weight	347.39
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.1
Synonyms	(2S,4S)-1-(5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carbonyl)-4-fluoro-pyrrolidine-2-carboxylic acid amide BDBM221143 SCHEMBL15776565 US9303012, 69 AGFOWDLWXFQXDY-WFASDCNBSA-N
Inchi Key	AGFOWDLWXFQXDY-WFASDCNBSA-N
Inchi ID	InChI=1S/C18H22FN3O3/c19-12-7-15(16(20)23)22(8-12)18(24)14-6-5-13(11-3-4-11)17(21-14)25-9-10-1-2-10/h5-6,10-12,15H,1-4,7-9H2,(H2,20,23)/t12-,15-/m0/s1
PubChem CID	90203853
ChEMBL	CHEMBL3898811
IUPHAR	N/A
BindingDB	221143
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536059	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
536058	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360

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