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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Moperone
Molecular formula	C22H26FNO2
IUPAC name	1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]butan-1-one
Molecular weight	355.453
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	Methylperidol Moperonum [INN-Latin] R 1658 1-Butanone, 1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]- AKOS030254497 D02623 NSC_4249 ZINC538026 1-(3'-p-Fluorobenzoylpropyl)-4-hydroxy-4-p-tolylpiperidine 4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone Butyrophenone, 4'-fluoro-4-(4-hydroxy-4-p-tolylpiperidino)- gamma-(4-hydroxy-4-p-methylphenylpiperidino)-p-fluorobutyrophenone Luvatrena Moperone [INN] p-Fluoro-4-(4'-hydroxy-4'-p-methylphenylpiperidino)butyrophenone 1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]butan-1-one AC1L1HQP CHEMBL2104700 Moperona Mopiperone SCHEMBL34340 1050-79-9 API0003426 EINECS 213-887-6 L000665 Moperone (INN) omega-(4-Hydroxy-4-p-tolylpiperidino)-p-fluorobutyrophenone 1-(4-Fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone 4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone;4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone CAS_1050-79-9 Meperon Moperonum p-Fluoro-4-(4'-hydroxy-4'-p-tolylpiperidino)butyrophenone 1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-methylphenyl)-1-piperidinyl)- AGAHNABIDCTLHW-UHFFFAOYSA-N CTK8G1178 Moperona [INN-Spanish] NCGC00188430-01 UNII-OU730881W5 3871-82-7 (hydrochloride) BDBM81486 FT-0672517 Luvatren Moperone HCl OU730881W5 1-(4-Fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone # CHEBI:135500 [ Show all ]
Inchi Key	AGAHNABIDCTLHW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26FNO2/c1-17-4-8-19(9-5-17)22(26)12-15-24(16-13-22)14-2-3-21(25)18-6-10-20(23)11-7-18/h4-11,26H,2-3,12-16H2,1H3
PubChem CID	4249
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4686	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
4687	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555499	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
555500	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
4688	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
4685	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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