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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL10860
Molecular formula	C28H21NO6
IUPAC name	3-(1,3-benzodioxol-5-yl)-5-hydroxy-4-(isoquinolin-1-ylmethyl)-5-(4-methoxyphenyl)furan-2-one
Molecular weight	467.477
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM50057165 3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-ylmethyl-5-(4-methoxy-phenyl)-5H-furan-2-one
Inchi Key	AFZSZVWTPJVSMZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H21NO6/c1-32-20-9-7-19(8-10-20)28(31)22(15-23-21-5-3-2-4-17(21)12-13-29-23)26(27(30)35-28)18-6-11-24-25(14-18)34-16-33-24/h2-14,31H,15-16H2,1H3
PubChem CID	10671928
ChEMBL	CHEMBL10860
IUPHAR	N/A
BindingDB	50057165
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4670	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
4671	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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