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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL16222656
Molecular formula	C20H23ClN6O2S
IUPAC name	6-[2-tert-butyl-9-[(3-chloropyridin-2-yl)methyl]purin-6-yl]-2lambda6-thia-6-azaspiro[3.3]heptane 2,2-dioxide
Molecular weight	446.954
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.4
Synonyms	6-[2-tert-butyl-9-[(3-chloropyridin-2-yl)methyl]purin-6-yl]-2lambda6-thia-6-azaspiro[3.3]heptane 2,2-dioxide US9505762, 162 AELZTFHFDZRLAS-UHFFFAOYSA-N
Inchi Key	AELZTFHFDZRLAS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23ClN6O2S/c1-19(2,3)18-24-16-15(23-12-26(16)7-14-13(21)5-4-6-22-14)17(25-18)27-8-20(9-27)10-30(28,29)11-20/h4-6,12H,7-11H2,1-3H3
PubChem CID	117687337
ChEMBL	N/A
IUPHAR	N/A
BindingDB	259794
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536007	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
536006	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360

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