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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL135295
Molecular formula	C21H22N2OS
IUPAC name	3-(4-naphthalen-1-ylpiperazin-1-yl)-1-thiophen-3-ylpropan-1-one
Molecular weight	350.48
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-yl-propan-1-one 3-(4-(naphthalen-1-yl)piperazin-1-yl)-1-(thiophen-3-yl)propan-1-one BDBM50102373
Inchi Key	AEEDQVJYSPEPSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N2OS/c24-21(18-9-15-25-16-18)8-10-22-11-13-23(14-12-22)20-7-3-5-17-4-1-2-6-19(17)20/h1-7,9,15-16H,8,10-14H2
PubChem CID	11792177
ChEMBL	CHEMBL135295
IUPHAR	N/A
BindingDB	50102373
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3380	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
3381	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422

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