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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL215974
Molecular formula	C25H30Cl2F3N3O
IUPAC name	1-[4-[2-(1-aminopentyl)-4-(trifluoromethyl)phenyl]piperazin-1-yl]-3-(2,4-dichlorophenyl)propan-1-one
Molecular weight	516.43
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.0
Synonyms	BDBM50189236 1-(4-(2-(1-aminopentyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)propan-1-one
Inchi Key	ADRDTTJUTJRJPA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30Cl2F3N3O/c1-2-3-4-22(31)20-15-18(25(28,29)30)7-9-23(20)32-11-13-33(14-12-32)24(34)10-6-17-5-8-19(26)16-21(17)27/h5,7-9,15-16,22H,2-4,6,10-14,31H2,1H3
PubChem CID	44415522
ChEMBL	CHEMBL215974
IUPHAR	N/A
BindingDB	50189236
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3000	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332

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