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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2165330
Molecular formula	C24H22BrClN6O6S
IUPAC name	N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-chloro-5-methoxyphenoxy)pyrimidin-4-amine
Molecular weight	637.89
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	4.1
Synonyms	BDBM50395635 Benzylsulfamic acid [6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-amide SCHEMBL14380741 ADKWUFCPMCLUKI-UHFFFAOYSA-N
Inchi Key	ADKWUFCPMCLUKI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22BrClN6O6S/c1-35-18-7-8-19(26)20(11-18)38-21-22(32-39(33,34)31-12-16-5-3-2-4-6-16)29-15-30-23(21)36-9-10-37-24-27-13-17(25)14-28-24/h2-8,11,13-15,31H,9-10,12H2,1H3,(H,29,30,32)
PubChem CID	21041370
ChEMBL	CHEMBL2165330
IUPHAR	N/A
BindingDB	50395635
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2388	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
2389	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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