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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000086795
Molecular formula	C24H28ClN5O4
IUPAC name	N-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-3-(2-methoxyethyl)-2,4-dioxo-1H-quinazoline-7-carboxamide
Molecular weight	485.969
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.0
Synonyms	AC1MMAM9 MCULE-5395609344 N-[2-[4-(3-chlorophenyl)piperazino]ethyl]-2,4-diketo-3-(2-methoxyethyl)-1H-quinazoline-7-carboxamide CHEMBL1417144 MolPort-007-594-512 ZINC4005055 F6548-1185 N-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-3-(2-methoxyethyl)-2,4-bis(oxidanylidene)-1H-quinazoline-7-carboxamide AKOS001758824 N-{2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl}-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide cid_3235755 N-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide 892289-88-2 HMS2362I05 N-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-3-(2-methoxyethyl)-2,4-dioxo-1H-quinazoline-7-carboxamide BDBM30840 MLS001065472 SMR000022823 EU-0089709 N-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-3-(2-methoxyethyl)-2,4-dioxo-1H-quinazoline-7-carboxamide [ Show all ]
Inchi Key	ACVZMBHNSYAYKV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28ClN5O4/c1-34-14-13-30-23(32)20-6-5-17(15-21(20)27-24(30)33)22(31)26-7-8-28-9-11-29(12-10-28)19-4-2-3-18(25)16-19/h2-6,15-16H,7-14H2,1H3,(H,26,31)(H,27,33)
PubChem CID	3235755
ChEMBL	N/A
IUPHAR	N/A
BindingDB	30840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1982	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422

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