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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL282874
Molecular formula	C20H20N2O
IUPAC name	11,11-dimethyl-8,17-diazapentacyclo[10.7.1.02,7.08,20.014,19]icosa-1(19),2,4,6,12(20),13-hexaen-9-one
Molecular weight	304.393
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.5
Synonyms	7,7-Dimethyl-6,7,9,10,11,12-hexahydro-5H-4b,11-diazabenzo[a]aceanthrylene-5-one
Inchi Key	ACUBTKJTXUPFDJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2O/c1-20(2)10-17(23)22-16-6-4-3-5-13(16)18-14-11-21-8-7-12(14)9-15(20)19(18)22/h3-6,9,21H,7-8,10-11H2,1-2H3
PubChem CID	11066674
ChEMBL	CHEMBL282874
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1940	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
1941	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
1939	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
1942	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479

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