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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS003509449
Molecular formula	C38H53N5O4
IUPAC name	(5S)-5-benzyl-1-[(2S)-4-methyl-1-[(2S)-2-[[(6S)-6-(2-methylpropyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]pentan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione
Molecular weight	643.873
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.4
Synonyms	SMR002147580 CHEMBL2355721
Inchi Key	ABDBAGPWPRZDPO-CUPIEXAXSA-N
Inchi ID	InChI=1S/C38H53N5O4/c1-27(2)20-32-23-39-35(44)36(45)42(32)25-31-16-11-18-40(31)24-33(21-28(3)4)43-26-34(22-30-14-9-6-10-15-30)41(37(46)38(43)47)19-17-29-12-7-5-8-13-29/h5-10,12-15,27-28,31-34H,11,16-26H2,1-4H3,(H,39,44)/t31-,32-,33-,34-/m0/s1
PubChem CID	53300439
ChEMBL	CHEMBL2355721
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463037	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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