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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3394753
Molecular formula	C35H51FN4O4
IUPAC name	8-(cyclooctylmethyl)-3-[(2S)-3-[2-(3,4-dimethoxyphenyl)ethylamino]-2-hydroxypropyl]-1-(4-fluorophenyl)-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	610.815
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	6.2
Synonyms	BDBM50060893
Inchi Key	ABBBAYMZEUIFIL-HKBQPEDESA-N
Inchi ID	InChI=1S/C35H51FN4O4/c1-43-32-15-10-27(22-33(32)44-2)16-19-37-23-31(41)25-39-26-40(30-13-11-29(36)12-14-30)35(34(39)42)17-20-38(21-18-35)24-28-8-6-4-3-5-7-9-28/h10-15,22,28,31,37,41H,3-9,16-21,23-26H2,1-2H3/t31-/m0/s1
PubChem CID	118726271
ChEMBL	CHEMBL3394753
IUPHAR	N/A
BindingDB	50060893
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
441696	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
441698	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
441697	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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