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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tyr-Pro-Emp-Phe-NH2
Molecular formula	C35H43N5O5
IUPAC name	(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(2-ethyl-6-methylphenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Molecular weight	613.759
Hydrogen bond acceptor	6
Hydrogen bond donor	5
XlogP	3.8
Synonyms	CHEMBL375274 BDBM50212615 D0Y5TF
Inchi Key	AAXFHBRSEVMRCW-ORYMTKCHSA-N
Inchi ID	InChI=1S/C35H43N5O5/c1-3-25-12-7-9-22(2)27(25)21-30(33(43)38-29(32(37)42)20-23-10-5-4-6-11-23)39-34(44)31-13-8-18-40(31)35(45)28(36)19-24-14-16-26(41)17-15-24/h4-7,9-12,14-17,28-31,41H,3,8,13,18-21,36H2,1-2H3,(H2,37,42)(H,38,43)(H,39,44)/t28-,29-,30-,31-/m0/s1
PubChem CID	16736708
ChEMBL	CHEMBL375274
IUPHAR	N/A
BindingDB	50212615
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
591	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
592	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
593	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
594	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98

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