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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000730737
Molecular formula	C19H16FN5O3S2
IUPAC name	(6Z)-6-[[1-(4-fluorophenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
Molecular weight	445.487
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.8
Synonyms	(6Z)-6-[[1-(4-fluorophenyl)-2,5-dimethyl-pyrrol-3-yl]methylene]-5-imino-3-mesyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one cid_16194228 AB00578514-05 MolPort-007-623-354 (6Z)-5-azanylidene-6-[[1-(4-fluorophenyl)-2,5-dimethyl-pyrrol-3-yl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one SR-01000126107-1 (6Z)-6-[[1-(4-fluorophenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one HMS2588K16 AKOS001803174 SMR000309112 (6Z)-6-[[1-(4-fluorophenyl)-2,5-dimethyl-3-pyrrolyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one CHEMBL1482053 ZINC13574265 (6Z)-6-{[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene}-5-imino-3-(methylsulfonyl)-5,6-dihydro-7H-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one BDBM57883 SR-01000126107 [ Show all ]
Inchi Key	AATSFXAHBUYHMF-IAYHVCARSA-N
Inchi ID	InChI=1S/C19H16FN5O3S2/c1-10-8-12(11(2)24(10)14-6-4-13(20)5-7-14)9-15-16(21)25-18(22-17(15)26)29-23-19(25)30(3,27)28/h4-9,21H,1-3H3/b15-9-,21-16?
PubChem CID	16194228
ChEMBL	CHEMBL1482053
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463015	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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