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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1080117
Molecular formula	C27H28ClN5S
IUPAC name	5-[5-[3-[1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylquinoline
Molecular weight	490.066
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.5
Synonyms	BDBM50415697
Inchi Key	AAONJNLMLWRZJE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28ClN5S/c1-18-7-12-22-23(5-3-6-24(22)29-18)25-30-31-26(32(25)2)34-14-4-13-33-16-20-15-27(20,17-33)19-8-10-21(28)11-9-19/h3,5-12,20H,4,13-17H2,1-2H3
PubChem CID	44626740
ChEMBL	CHEMBL1080117
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
393	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
392	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
394	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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