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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	3-(5-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phenyl)piperazin-1-yl)pentyl)-1H-indole-5-carbonitrile
Molecular formula	C29H29F2N5O
IUPAC name	3-[5-[4-[4-(3,5-difluoro-2-oxopyridin-1-yl)phenyl]piperazin-1-yl]pentyl]-1H-indole-5-carbonitrile
Molecular weight	501.582
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.1
Synonyms	AABXZZAFWRPYLP-UHFFFAOYSA-N US9714232, 28 BDBM264115 SCHEMBL16855141
Inchi Key	AABXZZAFWRPYLP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29F2N5O/c30-23-17-27(31)29(37)36(20-23)25-8-6-24(7-9-25)35-14-12-34(13-15-35)11-3-1-2-4-22-19-33-28-10-5-21(18-32)16-26(22)28/h5-10,16-17,19-20,33H,1-4,11-15H2
PubChem CID	118190898
ChEMBL	N/A
IUPHAR	N/A
BindingDB	264115
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557308	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
557309	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422

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