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Name | Lysophosphatidic acid receptor 3 |
---|---|
Species | Homo sapiens (Human) |
Gene | LPAR3 |
Synonym | Lysophosphatidic acid receptor Edg-7 LPA3 receptor LPA-3 LPA receptor 3 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 [ Show all ] |
Disease | Fibrosis |
Length | 353 |
Amino acid sequence | MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS |
UniProt | Q9UBY5 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9UBY5 |
3D structure model | This predicted structure model is from GPCR-EXP Q9UBY5. |
BioLiP | N/A |
Therapeutic Target Database | T95923 |
ChEMBL | CHEMBL3250 |
IUPHAR | 274 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
3425 | CHEMBL485119 | C15H12N2O8 | 348.267 | 8 / 5 | -0.1 | Yes |
553284 | Farnesyl monophosphate | C15H27O4P | 302.351 | 4 / 2 | 3.7 | Yes |
17213 | CHEMBL193196 | C21H42FO6P | 440.533 | 7 / 2 | 6.4 | No |
17532 | CHEMBL357053 | C22H45O6PS | 468.63 | 7 / 2 | 8.4 | No |
17541 | CHEMBL153043 | C22H45O6PS | 468.63 | 7 / 2 | 8.4 | No |
17546 | CHEMBL2017139 | C22H45O6PS | 468.63 | 7 / 2 | 8.4 | No |
20485 | NAEPA | C20H40NO5P | 405.516 | 5 / 3 | 5.2 | No |
25663 | CHEMBL189296 | C14H31O3PS | 310.433 | 4 / 2 | 6.8 | No |
25976 | CHEMBL2182062 | C31H31N3O4 | 509.606 | 5 / 1 | 5.8 | No |
29256 | CHEMBL313413 | C36H54NO6P | 627.803 | 6 / 3 | 9.3 | No |
29833 | LPA2 antagonist 1 | C20H23Cl2N5O2S2 | 500.457 | 8 / 1 | 4.3 | No |
442851 | CHEMBL2182024 | C25H27N3O4 | 433.508 | 5 / 2 | 4.5 | Yes |
33971 | Tetradecylphosphonic acid | C14H31O3P | 278.373 | 3 / 2 | 5.1 | No |
34950 | CHEMBL117529 | C21H40NO5P | 417.527 | 5 / 3 | 4.9 | Yes |
43194 | CHEMBL2182026 | C25H25N3O4 | 431.492 | 5 / 2 | 4.1 | Yes |
47586 | CHEMBL215722 | C22H41F2O5P | 454.536 | 7 / 1 | 8.2 | No |
49425 | CHEMBL182446 | C36H57N2O8P | 676.832 | 9 / 3 | 7.5 | No |
49613 | CHEMBL265967 | C34H53N2O7P | 632.779 | 8 / 3 | 7.7 | No |
50272 | CHEMBL2182042 | C26H24N4O4 | 456.502 | 6 / 2 | 4.2 | Yes |
51245 | CHEMBL202242 | C19H37O7PS | 440.532 | 8 / 2 | 6.0 | No |
51248 | CHEMBL202361 | C19H37O7PS | 440.532 | 8 / 2 | 6.0 | No |
537349 | CHEMBL3975893 | C33H32ClNO6 | 574.07 | 6 / 1 | 7.2 | No |
57810 | CHEMBL360064 | C32H51N2O5P | 574.743 | 6 / 3 | 7.9 | No |
60442 | CHEMBL2182030 | C28H25FN4O4 | 500.53 | 7 / 2 | 5.1 | No |
65690 | CHEMBL404575 | C19H18N2O3 | 322.364 | 4 / 1 | 3.9 | Yes |
67556 | CHEMBL187459 | C18H37O3PS | 364.525 | 4 / 2 | 8.1 | No |
71930 | CHEMBL328474 | C30H48NO6P | 549.689 | 6 / 3 | 7.3 | No |
72937 | SCHEMBL8438208 | C10H23O3P | 222.265 | 3 / 2 | N/A | N/A |
75268 | (2S)-OMPT | C22H43O6PS | 466.614 | 7 / 2 | 7.5 | No |
472301 | CHEMBL3621961 | C22H45O5PS | 452.631 | 6 / 2 | 7.8 | No |
76230 | alkyl OMPT | C22H45O5PS | 452.631 | 6 / 2 | 7.8 | No |
77231 | CHEMBL3218459 | C35H54F3N2O7P | 702.793 | 11 / 3 | 9.7 | No |
77519 | CHEMBL2182028 | C26H24N4O4 | 456.502 | 6 / 2 | 4.6 | Yes |
79843 | CHEMBL2182037 | C29H29N5O5S | 559.641 | 7 / 2 | 4.3 | No |
79956 | CHEMBL192861 | C21H39F2O6P | 456.508 | 8 / 2 | 6.7 | No |
82533 | CHEMBL195383 | C19H37F2O6P | 430.47 | 8 / 2 | 6.6 | No |
86135 | CHEMBL190349 | C12H25O4P | 264.302 | 4 / 2 | 3.1 | Yes |
86327 | CHEMBL2182063 | C29H27N3O4 | 481.552 | 5 / 2 | 5.1 | No |
86863 | 36840-10-5 | C20H16N2O6 | 380.356 | 6 / 4 | 1.4 | Yes |
89072 | CHEMBL314553 | C39H60NO7P | 685.883 | 7 / 3 | 11.1 | No |
89771 | CHEMBL2182061 | C27H25N3O4 | 455.514 | 5 / 2 | 4.8 | Yes |
91233 | CHEMBL117663 | C21H41FNO4P | 421.534 | 5 / 3 | 6.1 | No |
93763 | CHEMBL203986 | C19H41O6P | 396.505 | 6 / 2 | 5.1 | No |
93765 | CHEMBL202243 | C19H41O6P | 396.505 | 6 / 2 | 5.1 | No |
96493 | CHEMBL2182057 | C19H17ClFN3O2 | 373.812 | 4 / 1 | 4.4 | Yes |
96551 | CHEMBL2182032 | C29H25F3N4O4 | 550.538 | 9 / 2 | 5.9 | No |
100155 | CHEMBL2182055 | C25H23N3O2 | 397.478 | 3 / 1 | 5.3 | No |
445645 | 325850-81-5 | C22H17NO4S | 391.441 | 5 / 1 | 4.2 | Yes |
102485 | CHEMBL94245 | C34H51N2O7P | 630.763 | 8 / 4 | 8.0 | No |
104953 | CHEMBL2182045 | C25H28N4O4 | 448.523 | 6 / 2 | 4.5 | Yes |
111766 | CHEMBL191411 | C34H54NO6P | 603.781 | 6 / 3 | 9.7 | No |
113883 | CHEMBL604677 | C21H12N2O7 | 404.334 | 7 / 1 | 3.3 | Yes |
114528 | CHEMBL211465 | C20H39O4PS | 406.562 | 5 / 1 | 8.1 | No |
117460 | CHEMBL2182047 | C29H25F3N4O4 | 550.538 | 9 / 2 | 5.5 | No |
117463 | CHEMBL2182046 | C29H25F3N4O4 | 550.538 | 9 / 2 | 5.5 | No |
538875 | CHEMBL3969018 | C29H25F3N4O4 | 550.538 | 9 / 2 | 5.5 | No |
122948 | L-NASPA | C19H38NO7P | 423.487 | 7 / 4 | 4.7 | Yes |
124786 | CHEMBL183143 | C35H55N2O7P | 646.806 | 8 / 3 | 8.0 | No |
127642 | CHEMBL482498 | C26H20N2O8 | 488.452 | 8 / 4 | 2.9 | Yes |
127778 | CHEMBL94011 | C28H48NO6P | 525.667 | 6 / 3 | 7.2 | No |
129050 | CHEMBL2182038 | C28H26N8O2 | 506.57 | 7 / 2 | 5.0 | No |
130629 | CID 44392848 | C35H54NO6P | 615.792 | 6 / 4 | 8.5 | No |
135411 | CHEMBL2182050 | C30H28F3N5O5S | 627.639 | 10 / 2 | 4.8 | No |
138417 | CHEMBL2182044 | C28H25FN4O4 | 500.53 | 7 / 2 | 4.7 | No |
140723 | Thiophosphoric acid decyl ester | C10H23O3PS | 254.325 | 4 / 2 | 4.7 | Yes |
141050 | dodecyl-thiophosphate | C12H27O3PS | 282.379 | 4 / 2 | 5.8 | No |
141527 | CHEMBL441066 | C32H50NO6P | 575.727 | 6 / 3 | 8.6 | No |
141740 | CHEMBL432821 | C30H46NO6P | 547.673 | 6 / 3 | 7.5 | No |
144143 | CHEMBL362053 | C36H57N2O7P | 660.833 | 8 / 3 | 8.4 | No |
144146 | CHEMBL181917 | C36H57N2O7P | 660.833 | 8 / 3 | 8.4 | No |
145190 | CHEMBL329422 | C32H56NO6P | 581.775 | 6 / 3 | 8.9 | No |
145192 | CHEMBL92593 | C32H56NO6P | 581.775 | 6 / 3 | 8.9 | No |
146422 | CHEMBL482505 | C17H33O8P | 396.417 | 8 / 2 | 3.2 | Yes |
146755 | CHEMBL2182040 | C27H24N4O4 | 468.513 | 6 / 2 | 4.6 | Yes |
151959 | CHEMBL187402 | C14H29O3PS | 308.417 | 4 / 2 | 5.9 | No |
153097 | CHEMBL360399 | C33H51N2O6P | 602.753 | 7 / 3 | 7.7 | No |
153098 | CHEMBL360397 | C33H51N2O6P | 602.753 | 7 / 3 | 7.7 | No |
159720 | CHEMBL190771 | C19H38FO6P | 412.479 | 7 / 2 | 6.1 | No |
162858 | CHEMBL2335048 | C22H47O5PS | 454.647 | 6 / 2 | 8.8 | No |
162863 | CHEMBL2335047 | C22H47O5PS | 454.647 | 6 / 2 | 8.8 | No |
162866 | CHEMBL2335052 | C22H47O5PS | 454.647 | 6 / 2 | 8.8 | No |
163620 | CHEMBL2335050 | C21H44NaO5PS | 462.602 | 6 / 1 | N/A | N/A |
164229 | CHEMBL2182065 | C29H26FN3O4 | 499.542 | 6 / 2 | 5.2 | No |
164313 | CHEMBL188081 | C10H21O4P | 236.248 | 4 / 2 | 2.2 | Yes |
562568 | SCHEMBL16706497 | C19H18BrN3O2 | 400.276 | 4 / 0 | 3.8 | Yes |
550008 | CHEMBL3976990 | C19H18BrN3O2 | 400.276 | 4 / 0 | 3.8 | Yes |
168845 | alpha-fluoromethylenephosphonate | C23H44FO6P | 466.571 | 7 / 2 | 6.6 | No |
171084 | CHEMBL482506 | C17H33O7PS | 412.478 | 8 / 2 | 4.9 | Yes |
172974 | VPC32183 | C33H51N2O6P | 602.753 | 7 / 3 | 7.7 | No |
172978 | CHEMBL360727 | C33H51N2O6P | 602.753 | 7 / 3 | 7.7 | No |
176340 | Tetradecyl dihydrogen phosphate | C14H31O4P | 294.372 | 4 / 2 | 5.1 | No |
178099 | CHEMBL2335051 | C22H44NaO6PS | 490.612 | 7 / 1 | N/A | N/A |
179007 | CHEMBL92452 | C24H34NO6P | 463.511 | 6 / 3 | 4.2 | Yes |
180346 | CHEMBL2182033 | C25H28N4O4 | 448.523 | 6 / 2 | 4.9 | Yes |
181599 | CHEMBL204037 | C19H39N2O6P | 422.503 | 6 / 4 | 3.6 | Yes |
181600 | CHEMBL202251 | C19H39N2O6P | 422.503 | 6 / 4 | 3.6 | Yes |
184849 | CHEMBL2182031 | C29H25F3N4O4 | 550.538 | 9 / 2 | 5.9 | No |
188631 | CHEMBL91168 | C34H50NO6P | 599.749 | 6 / 3 | 8.0 | No |
189413 | CHEMBL192107 | C21H42FO6P | 440.533 | 7 / 2 | 6.4 | No |
190301 | Ki16425 | C23H23ClN2O5S | 474.956 | 7 / 2 | 4.5 | Yes |
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