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GPCR

NameLysophosphatidic acid receptor 3
SpeciesHomo sapiens (Human)
GeneLPAR3
SynonymLysophosphatidic acid receptor Edg-7
LPA3 receptor
LPA-3
LPA receptor 3
endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7
[ Show all ]
DiseaseFibrosis
Length353
Amino acid sequenceMNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
UniProtQ9UBY5
Protein Data BankN/A
GPCR-HGmod modelQ9UBY5
3D structure modelThis predicted structure model is from GPCR-EXP Q9UBY5.
BioLiPN/A
Therapeutic Target DatabaseT95923
ChEMBLCHEMBL3250
IUPHAR274
DrugBankN/A

Known ligands

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Total entries: 229
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
34252D structureCHEMBL485119C15H12N2O8348.2678 / 5-0.1Yes
5532842D structureFarnesyl monophosphateC15H27O4P302.3514 / 23.7Yes
172132D structureCHEMBL193196C21H42FO6P440.5337 / 26.4No
175322D structureCHEMBL357053C22H45O6PS468.637 / 28.4No
175412D structureCHEMBL153043C22H45O6PS468.637 / 28.4No
175462D structureCHEMBL2017139C22H45O6PS468.637 / 28.4No
204852D structureNAEPAC20H40NO5P405.5165 / 35.2No
256632D structureCHEMBL189296C14H31O3PS310.4334 / 26.8No
259762D structureCHEMBL2182062C31H31N3O4509.6065 / 15.8No
292562D structureCHEMBL313413C36H54NO6P627.8036 / 39.3No
298332D structureLPA2 antagonist 1C20H23Cl2N5O2S2500.4578 / 14.3No
4428512D structureCHEMBL2182024C25H27N3O4433.5085 / 24.5Yes
339712D structureTetradecylphosphonic acidC14H31O3P278.3733 / 25.1No
349502D structureCHEMBL117529C21H40NO5P417.5275 / 34.9Yes
431942D structureCHEMBL2182026C25H25N3O4431.4925 / 24.1Yes
475862D structureCHEMBL215722C22H41F2O5P454.5367 / 18.2No
494252D structureCHEMBL182446C36H57N2O8P676.8329 / 37.5No
496132D structureCHEMBL265967C34H53N2O7P632.7798 / 37.7No
502722D structureCHEMBL2182042C26H24N4O4456.5026 / 24.2Yes
512452D structureCHEMBL202242C19H37O7PS440.5328 / 26.0No
512482D structureCHEMBL202361C19H37O7PS440.5328 / 26.0No
5373492D structureCHEMBL3975893C33H32ClNO6574.076 / 17.2No
578102D structureCHEMBL360064C32H51N2O5P574.7436 / 37.9No
604422D structureCHEMBL2182030C28H25FN4O4500.537 / 25.1No
656902D structureCHEMBL404575C19H18N2O3322.3644 / 13.9Yes
675562D structureCHEMBL187459C18H37O3PS364.5254 / 28.1No
719302D structureCHEMBL328474C30H48NO6P549.6896 / 37.3No
729372D structureSCHEMBL8438208C10H23O3P222.2653 / 2N/AN/A
752682D structure(2S)-OMPTC22H43O6PS466.6147 / 27.5No
4723012D structureCHEMBL3621961C22H45O5PS452.6316 / 27.8No
762302D structurealkyl OMPTC22H45O5PS452.6316 / 27.8No
772312D structureCHEMBL3218459C35H54F3N2O7P702.79311 / 39.7No
775192D structureCHEMBL2182028C26H24N4O4456.5026 / 24.6Yes
798432D structureCHEMBL2182037C29H29N5O5S559.6417 / 24.3No
799562D structureCHEMBL192861C21H39F2O6P456.5088 / 26.7No
825332D structureCHEMBL195383C19H37F2O6P430.478 / 26.6No
861352D structureCHEMBL190349C12H25O4P264.3024 / 23.1Yes
863272D structureCHEMBL2182063C29H27N3O4481.5525 / 25.1No
868632D structure36840-10-5C20H16N2O6380.3566 / 41.4Yes
890722D structureCHEMBL314553C39H60NO7P685.8837 / 311.1No
897712D structureCHEMBL2182061C27H25N3O4455.5145 / 24.8Yes
912332D structureCHEMBL117663C21H41FNO4P421.5345 / 36.1No
937632D structureCHEMBL203986C19H41O6P396.5056 / 25.1No
937652D structureCHEMBL202243C19H41O6P396.5056 / 25.1No
964932D structureCHEMBL2182057C19H17ClFN3O2373.8124 / 14.4Yes
965512D structureCHEMBL2182032C29H25F3N4O4550.5389 / 25.9No
1001552D structureCHEMBL2182055C25H23N3O2397.4783 / 15.3No
4456452D structure325850-81-5C22H17NO4S391.4415 / 14.2Yes
1024852D structureCHEMBL94245C34H51N2O7P630.7638 / 48.0No
1049532D structureCHEMBL2182045C25H28N4O4448.5236 / 24.5Yes
1117662D structureCHEMBL191411C34H54NO6P603.7816 / 39.7No
1138832D structureCHEMBL604677C21H12N2O7404.3347 / 13.3Yes
1145282D structureCHEMBL211465C20H39O4PS406.5625 / 18.1No
1174602D structureCHEMBL2182047C29H25F3N4O4550.5389 / 25.5No
1174632D structureCHEMBL2182046C29H25F3N4O4550.5389 / 25.5No
5388752D structureCHEMBL3969018C29H25F3N4O4550.5389 / 25.5No
1229482D structureL-NASPAC19H38NO7P423.4877 / 44.7Yes
1247862D structureCHEMBL183143C35H55N2O7P646.8068 / 38.0No
1276422D structureCHEMBL482498C26H20N2O8488.4528 / 42.9Yes
1277782D structureCHEMBL94011C28H48NO6P525.6676 / 37.2No
1290502D structureCHEMBL2182038C28H26N8O2506.577 / 25.0No
1306292D structureCID 44392848C35H54NO6P615.7926 / 48.5No
1354112D structureCHEMBL2182050C30H28F3N5O5S627.63910 / 24.8No
1384172D structureCHEMBL2182044C28H25FN4O4500.537 / 24.7No
1407232D structureThiophosphoric acid decyl esterC10H23O3PS254.3254 / 24.7Yes
1410502D structuredodecyl-thiophosphateC12H27O3PS282.3794 / 25.8No
1415272D structureCHEMBL441066C32H50NO6P575.7276 / 38.6No
1417402D structureCHEMBL432821C30H46NO6P547.6736 / 37.5No
1441432D structureCHEMBL362053C36H57N2O7P660.8338 / 38.4No
1441462D structureCHEMBL181917C36H57N2O7P660.8338 / 38.4No
1451902D structureCHEMBL329422C32H56NO6P581.7756 / 38.9No
1451922D structureCHEMBL92593C32H56NO6P581.7756 / 38.9No
1464222D structureCHEMBL482505C17H33O8P396.4178 / 23.2Yes
1467552D structureCHEMBL2182040C27H24N4O4468.5136 / 24.6Yes
1519592D structureCHEMBL187402C14H29O3PS308.4174 / 25.9No
1530972D structureCHEMBL360399C33H51N2O6P602.7537 / 37.7No
1530982D structureCHEMBL360397C33H51N2O6P602.7537 / 37.7No
1597202D structureCHEMBL190771C19H38FO6P412.4797 / 26.1No
1628582D structureCHEMBL2335048C22H47O5PS454.6476 / 28.8No
1628632D structureCHEMBL2335047C22H47O5PS454.6476 / 28.8No
1628662D structureCHEMBL2335052C22H47O5PS454.6476 / 28.8No
1636202D structureCHEMBL2335050C21H44NaO5PS462.6026 / 1N/AN/A
1642292D structureCHEMBL2182065C29H26FN3O4499.5426 / 25.2No
1643132D structureCHEMBL188081C10H21O4P236.2484 / 22.2Yes
5625682D structureSCHEMBL16706497C19H18BrN3O2400.2764 / 03.8Yes
5500082D structureCHEMBL3976990C19H18BrN3O2400.2764 / 03.8Yes
1688452D structurealpha-fluoromethylenephosphonateC23H44FO6P466.5717 / 26.6No
1710842D structureCHEMBL482506C17H33O7PS412.4788 / 24.9Yes
1729742D structureVPC32183C33H51N2O6P602.7537 / 37.7No
1729782D structureCHEMBL360727C33H51N2O6P602.7537 / 37.7No
1763402D structureTetradecyl dihydrogen phosphateC14H31O4P294.3724 / 25.1No
1780992D structureCHEMBL2335051C22H44NaO6PS490.6127 / 1N/AN/A
1790072D structureCHEMBL92452C24H34NO6P463.5116 / 34.2Yes
1803462D structureCHEMBL2182033C25H28N4O4448.5236 / 24.9Yes
1815992D structureCHEMBL204037C19H39N2O6P422.5036 / 43.6Yes
1816002D structureCHEMBL202251C19H39N2O6P422.5036 / 43.6Yes
1848492D structureCHEMBL2182031C29H25F3N4O4550.5389 / 25.9No
1886312D structureCHEMBL91168C34H50NO6P599.7496 / 38.0No
1894132D structureCHEMBL192107C21H42FO6P440.5337 / 26.4No
1903012D structureKi16425C23H23ClN2O5S474.9567 / 24.5Yes

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