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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL482498
Molecular formula	C26H20N2O8
IUPAC name	(E)-4-[4-[3-[4-[[(E)-3-carboxyprop-2-enoyl]amino]phenoxy]phenoxy]anilino]-4-oxobut-2-enoic acid
Molecular weight	488.452
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	2.9
Synonyms	3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid AC1M4JFJ ZINC2924824 (2E,2'E)-4,4'-[benzene-1,3-diylbis(oxybenzene-4,1-diylimino)]bis(4-oxobut-2-enoic acid) BIM-0026004.P001 4,4''-(4,4''-(1,3-phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl)bis(4-oxobut-2-enoic acid) MolPort-001-015-587 AKOS003244689 (E)-4-[4-[3-[4-[[(E)-4-hydroxy-4-oxobut-2-enoyl]amino]phenoxy]phenoxy]anilino]-4-oxobut-2-enoic acid STK155992 BDBM50271765 [ Show all ]
Inchi Key	HZFPOTBCYPWQSH-QUMQEAAQSA-N
Inchi ID	InChI=1S/C26H20N2O8/c29-23(12-14-25(31)32)27-17-4-8-19(9-5-17)35-21-2-1-3-22(16-21)36-20-10-6-18(7-11-20)28-24(30)13-15-26(33)34/h1-16H,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/b14-12+,15-13+
PubChem CID	2260227
ChEMBL	CHEMBL482498
IUPHAR	N/A
BindingDB	50271765
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
127641	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
127640	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
127642	Lysophosphatidic acid receptor 3	Q9UBY5	LPAR3	Homo sapiens (Human)	353

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