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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 3
Species	Homo sapiens (Human)
Gene	LPAR3
Synonym	Lysophosphatidic acid receptor Edg-7 LPA3 receptor LPA-3 LPA receptor 3 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 Edg7 [ Show all ]
Disease	Fibrosis
Length	353
Amino acid sequence	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
UniProt	Q9UBY5
Protein Data Bank	N/A
GPCR-HGmod model	Q9UBY5
3D structure model	This predicted structure model is from GPCR-EXP Q9UBY5.
BioLiP	N/A
Therapeutic Target Database	T95923
ChEMBL	CHEMBL3250
IUPHAR	274
DrugBank	N/A

Ligand

Name	CHEMBL360064
Molecular formula	C32H51N2O5P
IUPAC name	[(3S)-3-(hexadecanoylamino)-4-[4-(pyridin-2-ylmethoxy)phenyl]butyl]phosphonic acid
Molecular weight	574.743
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	7.9
Synonyms	{(S)-3-Hexadecanoylamino-4-[4-(pyridin-2-ylmethoxy)-phenyl]-butyl}-phosphonic acid BDBM50150004
Inchi Key	DEJKWCWVWGRHDH-GDLZYMKVSA-N
Inchi ID	InChI=1S/C32H51N2O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-32(35)34-29(23-25-40(36,37)38)26-28-19-21-31(22-20-28)39-27-30-17-15-16-24-33-30/h15-17,19-22,24,29H,2-14,18,23,25-27H2,1H3,(H,34,35)(H2,36,37,38)/t29-/m1/s1
PubChem CID	44392834
ChEMBL	CHEMBL360064
IUPHAR	N/A
BindingDB	50150004
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1050.0 nM	PMID15225728	BindingDB,ChEMBL

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