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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	36840-10-5
Molecular formula	C20H16N2O6
IUPAC name	(E)-4-[4-[4-[[(E)-3-carboxyprop-2-enoyl]amino]phenyl]anilino]-4-oxobut-2-enoic acid
Molecular weight	380.356
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.4
Synonyms	3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acid AKOS000485739 MolPort-001-823-423 4,4'-([1,1'-Biphenyl]-4,4'-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) BDBM50271764 STK026581 2545AJ CHEMBL482497 ARONIS018656 SCHEMBL13381223 (2E,2'E)-4,4'-(biphenyl-4,4'-diyldiimino)bis(4-oxobut-2-enoic acid) 4,4'-[4,4'-biphenyldiyldi(imino)]bis(4-oxo-2-butenoic acid) BIM-0014380.P001 ZINC833024 3-[4''-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acid AC1LL87D E,E-3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acid 4,4'-(4,4'-Biphenyldiyldiimino)bis(4-oxo-2-butenoic acid) BAS 00548842 SMSF0004862 (E)-4-[4-[4-[[(E)-4-hydroxy-4-oxobut-2-enoyl]amino]phenyl]anilino]-4-oxobut-2-enoic acid 4488-19-1 [ Show all ]
Inchi Key	FTLRWRKPUWMOMS-WGDLNXRISA-N
Inchi ID	InChI=1S/C20H16N2O6/c23-17(9-11-19(25)26)21-15-5-1-13(2-6-15)14-3-7-16(8-4-14)22-18(24)10-12-20(27)28/h1-12H,(H,21,23)(H,22,24)(H,25,26)(H,27,28)/b11-9+,12-10+
PubChem CID	1105689
ChEMBL	CHEMBL482497
IUPHAR	N/A
BindingDB	50271764
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
86862	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
86861	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
86863	Lysophosphatidic acid receptor 3	Q9UBY5	LPAR3	Homo sapiens (Human)	353

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