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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Lysophosphatidic acid receptor 3
Species	Homo sapiens (Human)
Gene	LPAR3
Synonym	Lysophosphatidic acid receptor Edg-7 LPA3 receptor LPA-3 LPA receptor 3 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 Edg7 [ Show all ]
Disease	Fibrosis
Length	353
Amino acid sequence	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
UniProt	Q9UBY5
Protein Data Bank	N/A
GPCR-HGmod model	Q9UBY5
3D structure model	This predicted structure model is from GPCR-EXP Q9UBY5.
BioLiP	N/A
Therapeutic Target Database	T95923
ChEMBL	CHEMBL3250
IUPHAR	274
DrugBank	N/A

Ligand

Name	Tetradecylphosphonic acid
Molecular formula	C14H31O3P
IUPAC name	tetradecylphosphonic acid
Molecular weight	278.373
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.1
Synonyms	C-52694 EINECS 225-118-1 n-Tetradecylphosphonic acid SR-01000946789 Tetradecylphosphonic acid, 97% 1-Tetradecanephosphonic acid AKOS015918250 CHEMBL190999 HMS3650I03 P-tetradecyl-Phosphonic acid Tetradecanephosphonic acid ZINC36178975 4-04-00-03566 (Beilstein Handbook Reference) BRN 1784271 DB-070750 MFCD00015834 RT-004112 tetradecylphosphonate AC1L2V5G C14H31O3P F0001-1259 NSC-127409 SR-01000946789-1 Tetradecylphosphonic acid, 99+ % 1-Tetradecylphosphonic Acid BBL103226 CTK3J7960 I14-8487 Phosphonic acid, P-tetradecyl- Tetradecyl phosphonic acid 4671-75-4 BVQJQTMSTANITJ-UHFFFAOYSA-N DTXSID7063550 MolPort-006-116-374 SCHEMBL19906 ACM4671754 FT-0693992 NSC127409 STL557036 WLN: QPQO&14 1956AH BDBM50170846 D0P7GR LS-106793 Phosphonic acid, tetradecyl- Tetradecyl-phosphonic acid [ Show all ]
Inchi Key	BVQJQTMSTANITJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H31O3P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18(15,16)17/h2-14H2,1H3,(H2,15,16,17)
PubChem CID	78401
ChEMBL	CHEMBL190999
IUPHAR	N/A
BindingDB	50170846
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	3100.0 nM	PMID16033271	BindingDB,ChEMBL
Ki	1120.0 nM	PMID16033271	BindingDB,ChEMBL

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