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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LPA2 antagonist 1
Molecular formula	C20H23Cl2N5O2S2
IUPAC name	N-[(2S)-1-[4-(3,4-dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
Molecular weight	500.457
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.3
Synonyms	CS-3103 AKOS027314118 NCGC00390601-01 1017606-66-4 HY-18075 BCP11072 ZINC29126798 CHEMBL256470 BDBM50373826 [ Show all ]
Inchi Key	BPRNMVDTWIHULJ-AWEZNQCLSA-N
Inchi ID	InChI=1S/C20H23Cl2N5O2S2/c1-13-11-30-19-18(13)23-12-24-20(19)25-14(2)10-26-5-7-27(8-6-26)31(28,29)15-3-4-16(21)17(22)9-15/h3-4,9,11-12,14H,5-8,10H2,1-2H3,(H,23,24,25)/t14-/m0/s1
PubChem CID	24882686
ChEMBL	CHEMBL256470
IUPHAR	N/A
BindingDB	50373826
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29834	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
29831	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
29833	Lysophosphatidic acid receptor 3	Q9UBY5	LPAR3	Homo sapiens (Human)	353
29832	Lysophosphatidic acid receptor 5	Q9H1C0	LPAR5	Homo sapiens (Human)	372

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