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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 3
Species	Homo sapiens (Human)
Gene	LPAR3
Synonym	Lysophosphatidic acid receptor Edg-7 LPA3 receptor LPA-3 LPA receptor 3 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 Edg7 [ Show all ]
Disease	Fibrosis
Length	353
Amino acid sequence	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
UniProt	Q9UBY5
Protein Data Bank	N/A
GPCR-HGmod model	Q9UBY5
3D structure model	This predicted structure model is from GPCR-EXP Q9UBY5.
BioLiP	N/A
Therapeutic Target Database	T95923
ChEMBL	CHEMBL3250
IUPHAR	274
DrugBank	N/A

Ligand

Name	dodecyl-thiophosphate
Molecular formula	C12H27O3PS
IUPAC name	dodecoxy-dihydroxy-sulfanylidene-lambda5-phosphane
Molecular weight	282.379
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.8
Synonyms	SCHEMBL40052 D04KQT GTPL6990 CHEMBL191365 Thiophosphoric acid dodecyl ester dodecoxy-dihydroxy-sulfanylidenephosphorane BDBM50170860 Phosphorothioic acid, O-dodecyl ester D01LEG thiophosphoric acid o-dodecyl ester [ Show all ]
Inchi Key	ISWBBUXCFWZBKC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H27O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h2-12H2,1H3,(H2,13,14,17)
PubChem CID	10468943
ChEMBL	CHEMBL191365
IUPHAR	6990
BindingDB	50170860
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	28.0 nM	PMID16033271	BindingDB,ChEMBL
Ki	14.0 nM	PMID16033271	BindingDB,ChEMBL

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