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Name | Thromboxane A2 receptor |
---|---|
Species | Mus musculus (Mouse) |
Gene | Tbxa2r |
Synonym | Prostanoid TP receptor TP receptor TXA2-R |
Disease | N/A for non-human GPCRs |
Length | 341 |
Amino acid sequence | MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP |
UniProt | P30987 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1795181 |
IUPHAR | 346 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
5134 | CHEMBL65121 | C17H18ClNO4S | 367.844 | 5 / 2 | 3.2 | Yes |
15948 | CHEMBL2315052 | C24H23Cl2FN2O2 | 461.358 | 4 / 0 | 6.2 | No |
17797 | CHEMBL2315053 | C27H25Cl2FN2O2 | 499.407 | 4 / 1 | 7.0 | No |
30048 | CHEMBL2315056 | C26H17Cl4FN2O4S | 614.29 | 6 / 1 | 7.6 | No |
31492 | CHEMBL1829811 | C27H34ClNO4S | 504.082 | 5 / 1 | 6.2 | No |
51703 | CHEMBL1829802 | C19H17ClN2O5S | 420.864 | 7 / 3 | 2.7 | Yes |
63010 | AC1NQW7X | C21H36O5 | 368.514 | 5 / 4 | 2.9 | Yes |
63298 | 11,9-epoxymethano PGH2 | C20H32O4 | 336.472 | 4 / 2 | 3.4 | Yes |
67785 | thromboxane A2 | C20H32O5 | 352.471 | 5 / 2 | 3.4 | Yes |
78001 | 9,11-azo PGH2 | C20H32N2O3 | 348.487 | 4 / 3 | 3.7 | Yes |
81096 | BDBM50353639 | C21H22ClNO4S | 419.92 | 5 / 1 | 3.7 | Yes |
100245 | 15(R)-Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
553758 | VAPIPROST | C30H39NO4 | 477.645 | 5 / 2 | 2.8 | Yes |
103363 | BDBM50353641 | C21H22ClNO4S | 419.92 | 5 / 1 | 3.5 | Yes |
116632 | UNII-CQ5912425U | C20H14Cl2FNO3 | 406.234 | 5 / 1 | 5.5 | No |
120406 | BDBM50353638 | C20H20ClNO4S | 405.893 | 5 / 1 | 3.2 | Yes |
122364 | SCHEMBL14321839 | C21H22ClNO4S | 419.92 | 5 / 2 | 3.7 | Yes |
145870 | SCHEMBL2962411 | C23H21Cl2FN2O4S | 511.389 | 6 / 1 | 5.7 | No |
158754 | CHEMBL2315050 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.6 | No |
172406 | CHEMBL1829812 | C24H28ClNO4S | 462.001 | 5 / 2 | 4.5 | Yes |
184575 | CHEMBL2315059 | C26H17Cl4FN2O4S | 614.29 | 6 / 1 | 7.6 | No |
554259 | U 46619 | C21H34O4 | 350.499 | 4 / 2 | 3.9 | Yes |
194034 | CHEMBL2315055 | C26H18Cl3FN2O4S | 579.848 | 6 / 1 | 7.0 | No |
221418 | BDBM50353637 | C20H20ClNO4S | 405.893 | 5 / 1 | 3.2 | Yes |
226077 | CHEMBL1828642 | C17H20ClNO3S | 353.861 | 4 / 2 | 3.4 | Yes |
231261 | CHEMBL2315046 | C24H21Cl2FN2O2 | 459.342 | 4 / 1 | 6.0 | No |
233262 | CHEMBL2315057 | C27H21Cl2FN2O4S | 559.433 | 6 / 1 | 6.7 | No |
241241 | CHEMBL1829801 | C17H18ClN5O2S | 391.874 | 6 / 2 | 3.3 | Yes |
241392 | Pinane thromboxane A2 | C24H40O3 | 376.581 | 3 / 2 | 6.2 | No |
246932 | BDBM50353645 | C23H26ClNO4S | 447.974 | 5 / 1 | 4.5 | Yes |
554517 | STA2 | C21H34O3S | 366.56 | 4 / 2 | 4.9 | Yes |
268835 | CHEMBL1829809 | C26H32ClNO4S | 490.055 | 5 / 1 | 5.9 | No |
554619 | Domitroban | C20H27NO4S | 377.499 | 5 / 2 | 3.6 | Yes |
271228 | CHEMBL12114 | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
273340 | CID 56623795 | C22H29N3O3 | 383.492 | 4 / 3 | 3.9 | Yes |
277566 | 10alpha,11alpha-oxido PGA2 | C20H30O5 | 350.455 | 5 / 2 | 2.9 | Yes |
279603 | SCHEMBL14321925 | C20H20ClNO4S | 405.893 | 5 / 2 | 3.4 | Yes |
287141 | SCHEMBL14321291 | C21H22ClNO4S | 419.92 | 5 / 2 | 3.6 | Yes |
289014 | BDBM50353643 | C22H24ClNO4S | 433.947 | 5 / 1 | 4.1 | Yes |
295831 | Inolin | C19H23NO5 | 345.395 | 6 / 3 | 2.5 | Yes |
554741 | SQ-29548 | C21H29N3O4 | 387.48 | 5 / 4 | 0.3 | Yes |
314942 | CHEMBL2315049 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.6 | No |
325724 | CHEMBL2315051 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.2 | No |
328082 | 87893-54-7 | C20H30O4 | 334.456 | 4 / 2 | 3.9 | Yes |
555021 | I-BOP | C23H29IO5 | 512.384 | 5 / 2 | 4.0 | No |
360782 | CHEMBL1829813 | C28H34ClNO4S | 516.093 | 5 / 1 | 6.5 | No |
370208 | CHEMBL2315054 | C20H15Cl2FN2O2 | 405.25 | 4 / 1 | 4.8 | Yes |
387452 | BDBM82220 | C24H29FO4 | 400.49 | 5 / 2 | 4.3 | Yes |
390110 | Prostaglandin E2 | C20H32O5 | 352.471 | 5 / 3 | 2.8 | Yes |
410701 | prostaglandin h2 | C20H32O5 | 352.471 | 5 / 2 | 3.8 | Yes |
411005 | CHEMBL1829807 | C25H30ClNO4S | 476.028 | 5 / 1 | 5.5 | No |
413909 | UNII-B5J9G2N18M | C22H38O5 | 382.541 | 5 / 4 | 3.6 | Yes |
417540 | CHEMBL2315048 | C24H21Cl2FN2O2 | 459.342 | 4 / 1 | 6.2 | No |
423376 | arachidonic acid | C20H32O2 | 304.474 | 2 / 1 | 6.3 | No |
425921 | CHEMBL2315047 | C24H21Cl2FN2O2 | 459.342 | 4 / 0 | 5.9 | No |
429224 | SCHEMBL14321660 | C20H20ClNO4S | 405.893 | 5 / 2 | 3.2 | Yes |
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