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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Mus musculus (Mouse)
Gene	Tbxa2r
Synonym	Prostanoid TP receptor TP receptor TXA2-R
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
UniProt	P30987
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1795181
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL1829811
Molecular formula	C27H34ClNO4S
IUPAC name	4-chloro-N-[2-[3-[[4-(2-methylpropoxy)-2-oxo-3-propan-2-ylcyclopent-3-en-1-yl]methyl]phenyl]ethyl]benzenesulfonamide
Molecular weight	504.082
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.2
Synonyms	BDBM50353646 SCHEMBL14321753
Inchi Key	BRZOQIYHRHUAKO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34ClNO4S/c1-18(2)17-33-25-16-22(27(30)26(25)19(3)4)15-21-7-5-6-20(14-21)12-13-29-34(31,32)24-10-8-23(28)9-11-24/h5-11,14,18-19,22,29H,12-13,15-17H2,1-4H3
PubChem CID	54757770
ChEMBL	CHEMBL1829811
IUPHAR	N/A
BindingDB	50353646
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	259.0 nM	PMID21863799	BindingDB,ChEMBL

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