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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VAPIPROST
Molecular formula	C30H39NO4
IUPAC name	(Z)-7-[(1R,2R,3S,5S)-3-hydroxy-5-[(4-phenylphenyl)methoxy]-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid
Molecular weight	477.645
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	D03ZVW NCGC00025325-02 ZINC13719916 AKOS027378112 GR-32191 UNII-H84XT1COAU GTPL1976 Vapiprostum 85505-64-2 DTXSID6048256 SCHEMBL28550 (Z)-7-[(1R,2R,3S,5S)-3-hydroxy-5-[(4-phenylphenyl)methoxy]-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid BDBM50283049 GR-32191B 4-Heptenoic acid, 7-(5-((1,1'-biphenyl)-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl)-, (1R-(1alpha(Z),2beta,3beta,5alpha))- CHEMBL65030 H84XT1COAU Vapiprostum [Latin] AC1OCEXR GR 32191 SN-309 (Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-yl-cyclopentyl]-hept-4-enoic acid BRD-K02283807-003-01-4 GR32191 Vapiprost [INN:BAN] [ Show all ]
Inchi Key	GQGRDYWMOPRROR-XUSMOFMBSA-N
Inchi ID	InChI=1S/C30H39NO4/c32-27-21-28(35-22-23-15-17-25(18-16-23)24-11-5-3-6-12-24)26(13-7-1-2-8-14-29(33)34)30(27)31-19-9-4-10-20-31/h1-3,5-6,11-12,15-18,26-28,30,32H,4,7-10,13-14,19-22H2,(H,33,34)/b2-1-/t26-,27-,28-,30+/m0/s1
PubChem CID	6918030
ChEMBL	CHEMBL65030
IUPHAR	1976
BindingDB	50283049
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
102624	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343
553758	Thromboxane A2 receptor	P30987	Tbxa2r	Mus musculus (Mouse)	341

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