You can:
| Name | B2 bradykinin receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Bdkrb2 |
| Synonym | B2 receptor B2BKR B2BRA BK-2 receptor BK2R [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 396 |
| Amino acid sequence | MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSWLNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLLPLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTLLRLGVLSGCWNERAVDIVTQISSYVAYSNSCLNPLVYVIVGKRFRKKSREVYQAICRKGGCMGESVQMENSMGTLRTSISVDRQIHKLQDWAGNKQ |
| UniProt | P25023 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2501 |
| IUPHAR | 42 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 11755 |  CHEMBL542427 | C24H32Cl2N2O3 | 467.431 | 5 / 2 | N/A | N/A |
| 12845 |  CHEMBL163956 | C14H14N4O2S | 302.352 | 4 / 3 | 3.7 | Yes |
| 18874 |  CHEMBL552864 | C31H34Cl2N2O | 521.526 | 3 / 1 | N/A | No |
| 23387 |  CHEMBL2112220 | C35H42N8O6S | 702.831 | 9 / 4 | 5.1 | No |
| 35100 |  CHEMBL164968 | C14H15N3S | 257.355 | 2 / 3 | 3.3 | Yes |
| 46889 |  CHEMBL2372276 | C65H94N20O13 | 1363.59 | 17 / 16 | -4.7 | No |
| 47204 |  CHEMBL159623 | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
| 66813 |  CHEMBL351310 | C28H30N6O6S2 | 610.704 | 9 / 5 | 5.4 | No |
| 70533 |  CHEMBL162787 | C22H28N6O5S3 | 552.683 | 9 / 4 | 3.4 | No |
| 70537 |  CHEMBL159456 | C22H28N6O5S3 | 552.683 | 9 / 4 | 3.4 | No |
| 74484 |  CHEMBL162184 | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
| 81796 |  CHEMBL3038095 | C58H83N19O13S | 1286.48 | 18 / 15 | -6.7 | No |
| 82312 |  CHEMBL159469 | C21H24N6O6S2 | 520.579 | 9 / 6 | 3.1 | No |
| 84094 |  CHEMBL555653 | C27H30Cl2N2O3 | 501.448 | 5 / 2 | N/A | No |
| 93791 |  CHEMBL538523 | C27H32Cl2N2O2 | 487.465 | 4 / 1 | N/A | N/A |
| 96477 |  CHEMBL164848 | C21H21N5O4S2 | 471.55 | 7 / 4 | 4.2 | Yes |
| 99296 |  CHEMBL3038096 | C57H89N19O13S | 1280.52 | 18 / 16 | -6.2 | No |
| 107918 |  CHEMBL161426 | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.9 | No |
| 116070 |  CHEMBL2372283 | C60H91N19O13 | 1286.51 | 17 / 15 | -6.2 | No |
| 120497 |  CHEMBL162947 | C31H28N6O6S2 | 644.721 | 9 / 5 | 6.0 | No |
| 121910 |  CHEMBL543612 | C27H32Cl2N2O2 | 487.465 | 4 / 1 | N/A | N/A |
| 123227 |  CHEMBL558799 | C28H32Cl2N2O3 | 515.475 | 5 / 2 | N/A | No |
| 128228 |  CHEMBL1907654 | C32H40Cl2N8O5S2 | 751.743 | 10 / 4 | 5.8 | No |
| 128897 |  CHEMBL165238 | C15H15N3O3 | 285.303 | 3 / 2 | 2.6 | Yes |
| 129487 |  CHEMBL1907655 | C27H28N6O5S2 | 580.678 | 8 / 4 | 4.3 | No |
| 553941 |  Labradimil | C49H75N15O12S | 1098.29 | 17 / 13 | -5.8 | No |
| 131054 |  CHEMBL163840 | C15H15N3O2S | 301.364 | 4 / 4 | 3.4 | Yes |
| 136556 |  CHEMBL160092 | C19H20N6O6S2 | 492.525 | 9 / 6 | 2.9 | No |
| 137812 |  CHEMBL3038101 | C57H83N19O13S | 1274.47 | 18 / 16 | -6.5 | No |
| 139193 |  CHEMBL3038105 | C52H79N15O12S | 1138.36 | 18 / 13 | -5.5 | No |
| 141687 |  CHEMBL2372278 | C52H76N14O12S | 1121.33 | 15 / 11 | -1.9 | No |
| 147851 |  CHEMBL1907653 | C32H42ClN7O4S | 656.243 | 8 / 4 | 4.2 | No |
| 150321 |  CHEMBL164636 | C20H18N4O2S | 378.45 | 4 / 3 | 5.4 | No |
| 155097 |  CHEMBL3038100 | C58H88N18O13S | 1277.52 | 17 / 14 | -3.4 | No |
| 167072 |  CHEMBL1907652 | C34H46N8O5S2 | 710.913 | 10 / 4 | 5.2 | No |
| 207737 |  CHEMBL349817 | C21H19N5O3S | 421.475 | 5 / 4 | 4.3 | Yes |
| 211531 |  CHEMBL423803 | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
| 212280 |  CHEMBL542179 | C28H32Cl2N2O3 | 515.475 | 5 / 2 | N/A | No |
| 216566 |  CHEMBL2112698 | C51H77N19O13S2 | 1228.42 | 19 / 16 | -7.6 | No |
| 220091 |  CHEMBL1907651 | C33H44N8O5S2 | 696.886 | 10 / 4 | 4.9 | No |
| 221874 |  CHEMBL350109 | C22H22N4O4S2 | 470.562 | 7 / 3 | 4.2 | Yes |
| 227691 |  CHEMBL557336 | C28H32Cl2N2O3 | 515.475 | 5 / 2 | N/A | No |
| 229577 |  CHEMBL3038094 | C57H87N19O13S | 1278.5 | 18 / 15 | -7.0 | No |
| 230873 |  CHEMBL2112283 | C35H46N8O6S | 706.863 | 10 / 4 | 4.6 | No |
| 232680 |  CHEMBL163816 | C27H28N6O6S2 | 596.677 | 9 / 5 | 5.0 | No |
| 491892 |  CHEMBL3616880 | C91H123N23O18S | 1859.19 | 23 / 22 | -1.5 | No |
| 235731 |  CHEMBL163506 | C29H27N5O6S2 | 605.684 | 9 / 4 | 5.7 | No |
| 237580 |  CHEMBL350631 | C20H22N6O6S2 | 506.552 | 9 / 6 | 2.8 | No |
| 493275 |  CHEMBL3616879 | C85H121N23O18S2 | 1817.17 | 24 / 23 | -2.8 | No |
| 251648 |  CHEMBL165627 | C20H19N5O4S2 | 457.523 | 7 / 4 | 4.0 | Yes |
| 257542 |  CHEMBL423630 | C28H30N6O6S2 | 610.704 | 9 / 5 | 4.8 | No |
| 264727 |  CHEMBL164551 | C22H22N4O4S2 | 470.562 | 7 / 3 | 4.7 | Yes |
| 495995 |  CHEMBL3616881 | C82H115N23O18S | 1743.03 | 23 / 23 | -3.8 | No |
| 277919 |  CHEMBL2112221 | C34H40N8O5S2 | 704.865 | 9 / 4 | 5.4 | No |
| 279570 |  CHEMBL3038102 | C58H89N19O13S | 1292.53 | 18 / 15 | -6.5 | No |
| 280724 |  CHEMBL544088 | C30H32Cl2N2O | 507.499 | 3 / 1 | N/A | No |
| 498473 |  CHEMBL3616944 | C59H89N19O13S | 1304.54 | 18 / 15 | -6.4 | No |
| 287283 |  Icatibant | C59H89N19O13S | 1304.54 | 18 / 15 | -6.4 | No |
| 289638 |  BRADYKININ | C50H73N15O11 | 1060.23 | 14 / 12 | -4.8 | No |
| 292759 |  CHEMBL545482 | C31H34Cl2N2O | 521.526 | 3 / 1 | N/A | No |
| 293453 |  CHEMBL164361 | C25H25N5O3S | 475.567 | 5 / 3 | 5.5 | No |
| 293456 |  CHEMBL351387 | C25H25N5O3S | 475.567 | 5 / 3 | 5.5 | No |
| 295312 |  CHEMBL161703 | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
| 297468 |  CHEMBL349046 | C27H28N6O6S2 | 596.677 | 9 / 5 | 4.4 | No |
| 500072 |  CHEMBL3616878 | C82H114N22O17S | 1712.01 | 22 / 21 | -2.9 | No |
| 556664 |  BCTC | C20H25ClN4O | 372.897 | 3 / 1 | 4.3 | Yes |
| 556669 |  abt-702 | C22H19BrN6O | 463.339 | 7 / 1 | 3.4 | Yes |
| 307255 |  CHEMBL2112937 | C34H43F3N8O7S2 | 796.882 | 15 / 5 | N/A | No |
| 307256 |  CHEMBL2112044 | C34H43F3N8O7S2 | 796.882 | 15 / 5 | N/A | No |
| 314258 |  CHEMBL544783 | C30H32Cl2N2O | 507.499 | 3 / 1 | N/A | No |
| 454250 |  4-(Diphenylmethyl)-1-[4-(aminosulfonyl)-2-nitrophenyl]thiosemicarbazide | C20H19N5O4S2 | 457.523 | 7 / 4 | 4.0 | Yes |
| 334473 |  CHEMBL163974 | C26H26N6O6S2 | 582.65 | 9 / 5 | 4.5 | No |
| 339060 |  CHEMBL543848 | C23H30Cl2N2O3 | 453.404 | 5 / 2 | N/A | N/A |
| 339469 |  CHEMBL539533 | C31H32Cl2N2O3 | 551.508 | 5 / 2 | N/A | No |
| 340342 |  CHEMBL3038103 | C55H91N19O13S | 1258.51 | 18 / 16 | -6.3 | No |
| 343479 |  CHEMBL1907656 | C34H44N8O5S2 | 708.897 | 10 / 4 | 4.8 | No |
| 347906 |  CHEMBL3038106 | C58H89N19O14S | 1308.53 | 19 / 16 | -7.4 | No |
| 349689 |  CHEMBL3038099 | C58H89N19O13S | 1292.53 | 18 / 15 | -6.5 | No |
| 356013 |  CHEMBL165240 | C15H15N3O2S | 301.364 | 3 / 2 | 3.2 | Yes |
| 364197 |  CHEMBL543615 | C29H36Cl2N2O | 499.52 | 3 / 1 | N/A | N/A |
| 364329 |  CHEMBL545019 | C29H34Cl2N2O3 | 529.502 | 5 / 2 | N/A | No |
| 376022 |  CHEMBL163510 | C28H32N6O5S3 | 628.781 | 9 / 4 | 5.1 | No |
| 376026 |  CHEMBL351059 | C28H32N6O5S3 | 628.781 | 9 / 4 | 5.1 | No |
| 555282 |  Anatibant | C34H36Cl2N6O5S | 711.659 | 8 / 4 | 5.0 | No |
| 415871 |  CHEMBL352459 | C17H17N5O6S2 | 451.472 | 9 / 4 | 2.4 | Yes |
| 421794 |  CHEMBL3038104 | C52H79N15O12S | 1138.36 | 18 / 13 | -5.5 | No |
| 422105 |  CHEMBL164754 | C30H41N7O4S2 | 627.823 | 9 / 3 | 5.4 | No |
| 429032 |  CHEMBL431562 | C32H42N8O5S2 | 682.859 | 10 / 4 | 4.5 | No |
| 429035 |  Bradyzide | C32H42N8O5S2 | 682.859 | 10 / 4 | 4.5 | No |
| 429036 |  CHEMBL308468 | C32H42N8O5S2 | 682.859 | 10 / 4 | 4.5 | No |
| 430696 |  cetirizine | C21H25ClN2O3 | 388.892 | 5 / 1 | 1.7 | Yes |
| 433930 |  CHEMBL164914 | C14H14N4O2S | 302.352 | 4 / 3 | 3.2 | Yes |
| 440462 |  CHEMBL542672 | C23H30Cl2N2O3 | 453.404 | 5 / 2 | N/A | N/A |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417