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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B2 bradykinin receptor
Species	Rattus norvegicus (Rat)
Gene	Bdkrb2
Synonym	B2 receptor B2BKR B2BRA BK-2 receptor BK2R bradykinin receptor B2R [ Show all ]
Disease	N/A for non-human GPCRs
Length	396
Amino acid sequence	MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSWLNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLLPLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTLLRLGVLSGCWNERAVDIVTQISSYVAYSNSCLNPLVYVIVGKRFRKKSREVYQAICRKGGCMGESVQMENSMGTLRTSISVDRQIHKLQDWAGNKQ
UniProt	P25023
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2501
IUPHAR	42
DrugBank	N/A

Ligand

Name	CHEMBL164968
Molecular formula	C14H15N3S
IUPAC name	1-anilino-3-benzylthiourea
Molecular weight	257.355
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	3.3
Synonyms	(2-phenylhydrazino)[benzylamino]methane-1-thione phenyl-hydrazine-1-benzylamino-1-methanethione HMS2668C11 SR-01000060971-1 BDBM50085687 MLS000807221 1-anilino-3-benzylthiourea CTK0J2626 SMR000376374 AC1M58OL Hydrazinecarbothioamide, 2-phenyl-N-(phenylmethyl)- ST51030869 MolPort-004-281-126 27421-90-5 DTXSID00368091 SR-01000060971 AKOS001080232 MCULE-8855156378 ZINC3198665 [ Show all ]
Inchi Key	BXIJDLFIMVLRQN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H15N3S/c18-14(15-11-12-7-3-1-4-8-12)17-16-13-9-5-2-6-10-13/h1-10,16H,11H2,(H2,15,17,18)
PubChem CID	2324360
ChEMBL	CHEMBL164968
IUPHAR	N/A
BindingDB	50085687
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	100000.0 nM	PMID10715143	BindingDB,ChEMBL

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