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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DWAKANREVKRLQVRIAKAVKEGRWGKVKALQWLLTHSFYGKALAVKRVTDNSGSKTPGVDGITWSTQEQKAQAIKSLRR
RGYKPQPLRRVYIPKASGKQRPLGIPTTKDRAMQALYALALEPVAETTADRNSYGFRQGRCTADAAGQCFTVLGRSDCAK
YILDADITGCFDNISHEWLLDNIPLDKEVLRKWLKSGFVWKQQLFPGVISPMLANMTLDGMEELLKKHLRKQKVNLIRYA
DDFVVTGESKETLEKVTTVIQEFLKERGLTLSEEKTKVVHIEEGFDFLGWNIRKYGEKLLIKPAKKNIKAFHKKIRDALK
ELRTATQEAVIDTLNPIIKGWANYHRNQVSKRIFNRADDNIWHKLWRWAKRRHPNKPARWTKNKYFIKIGNRHWVFGTWR
SRYLIKAGDTRIQR

The query sequence (length=414) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fli:B 458 430 1.0000 0.9039 0.9628 0.0 6me0:C, 6mec:C
2 5hhk:B 289 266 0.2150 0.3080 0.3346 4.52e-33
3 5g2x:C 486 360 0.2633 0.2243 0.3028 1.41e-32 7d0f:C, 7d0g:C, 7d1a:C
4 7k9y:A 425 328 0.2512 0.2447 0.3171 8.69e-32 6ar1:A, 6ar1:D, 6ar3:A, 6ar3:D, 7k9y:D
5 8t2s:D 389 335 0.2319 0.2468 0.2866 7.41e-31 8t2r:D, 8t2t:D, 7uim:D, 7uin:D
6 8h2h:D 599 211 0.1643 0.1135 0.3223 9.92e-23
7 8h2h:D 599 59 0.0531 0.0367 0.3729 0.001
8 8ibw:C 922 267 0.1546 0.0694 0.2397 2.65e-06 8gh6:A, 8ibx:C, 8iby:C, 8ibz:C
9 8bgj:A 203 165 0.0966 0.1970 0.2424 0.005 8bgj:B, 8bgj:C
10 7v9x:A 314 209 0.0942 0.1242 0.1866 0.098 8qbk:A, 8qbk:U, 8qbk:K, 8qbk:P, 8qbl:A, 8qbl:K, 8qbl:P, 8qbl:I, 8qbl:U, 8qbl:Z, 8qbm:A, 8qbm:K, 8qbm:I, 8qbm:P, 8qbm:U, 8qbm:Z, 7v9u:A, 7v9u:B, 7v9x:B, 7xjg:A, 7xjg:B
11 7sr6:A 566 87 0.0628 0.0459 0.2989 0.10 7sr6:F, 7sr6:G
12 2y4o:A 433 42 0.0314 0.0300 0.3095 1.3 2y4o:B
13 4k50:A 460 135 0.0604 0.0543 0.1852 1.7 4k50:I, 4k50:E, 4k50:M, 1tp7:A
14 2y27:B 427 42 0.0314 0.0304 0.3095 2.4 2y27:A, 2y4n:A, 2y4n:B
15 1tme:3 230 28 0.0338 0.0609 0.5000 3.0
16 4xre:A 108 85 0.0556 0.2130 0.2706 3.4 4xre:B
17 8p4x:A 526 103 0.0652 0.0513 0.2621 3.4 8p4x:B
18 6zdp:A 683 62 0.0507 0.0307 0.3387 3.4
19 6azy:A 810 88 0.0556 0.0284 0.2614 4.0 6d00:1, 6d00:2, 6d00:3, 6d00:4, 6d00:5, 6d00:6
20 7rpx:E 590 67 0.0604 0.0424 0.3731 6.2 2hix:A, 7rpo:E, 7rpw:E
21 7smh:A 257 49 0.0290 0.0467 0.2449 6.6 8g1m:A, 7smh:B, 7smh:C, 7smh:D
22 8tg3:A 187 80 0.0580 0.1283 0.3000 6.7 8tg4:A
23 3e2v:A 363 39 0.0314 0.0358 0.3333 7.3 3e2v:B
24 5ujc:A 267 42 0.0411 0.0637 0.4048 9.1
25 5u1c:D 172 55 0.0386 0.0930 0.2909 9.5 5u1c:B
26 8ips:A 573 50 0.0411 0.0297 0.3400 10.0 8ipt:C, 8ipt:D, 7zda:C, 7zdb:C, 7zdc:C, 7zdf:C, 7zdg:C, 7zdk:C, 7zdl:C, 7zdt:C, 7zdu:C, 7zdw:C, 7ze5:C, 7zec:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218