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BioLiP
Download all results in tab-seperated text for 31 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3nga:A (2.71) BS01 3NG 2.7.11.1 GO:0004672 ... P68400 21093442 PDBbind: -logKd/Ki=8.00, Kd=10nM
    BindingDB: IC50=2000nM, Kd=0.562341nM, Ki=0.380000nM
    2 3nga:B (2.71) BS01 3NG 2.7.11.1 GO:0004672 ... P68400 21093442 BindingDB: IC50=2000nM, Kd=0.562341nM, Ki=0.380000nM
    3 3pe1:A (1.6) BS01 3NG 2.7.11.1 GO:0004672 ... P68400 21870818 MOAD: Ki=0.223nM
    PDBbind: -logKd/Ki=9.65, Ki=0.223nM
    BindingDB: IC50=2000nM, Kd=0.562341nM, Ki=0.380000nM
    4 5o11:A (2.4) BS01 3NG 2.7.11.1 GO:0004672 ... P11309 29042609 MOAD: ic50=0.216uM
    PDBbind: -logKd/Ki=6.67, IC50=0.216uM
    BindingDB: IC50=48nM
    5 6fyl:A (1.95) BS01 3NG 2.7.12.1 GO:0004672 ... P49760 29985556 MOAD: ic50=7nM
    PDBbind: -logKd/Ki=8.15, IC50=7nM
    BindingDB: IC50=4.0nM
    6 6fyp:A (2.29) BS01 3NG 2.7.12.1 GO:0004672 ... P49761 29985556 MOAD: ic50=143nM
    PDBbind: -logKd/Ki=6.84, IC50=143nM
    BindingDB: IC50=41nM
    7 6fyv:A (2.46) BS01 3NG 2.7.12.1 GO:0004672 ... Q9HAZ1 29985556 MOAD: ic50=11nM
    PDBbind: -logKd/Ki=7.96, IC50=11nM
    8 6hmb:A (1.04) BS01 3NG 2.7.11.1 GO:0000785 ... P19784 31559376 BindingDB: IC50=0.300000nM, Ki=0.220000nM
    9 6isj:A (2.3) BS01 3NG N/A GO:0004672 ... N/A N/A
    10 6k3l:B (2.09) BS01 3NG 2.7.11.1 GO:0004672 ... J9VNH4 31591414 MOAD: Kd=60.1nM
    11 6khd:A (2.7) BS01 3NG 2.7.12.1 GO:0004672 ... P49759 31531359
    12 6khd:B (2.7) BS01 3NG 2.7.12.1 GO:0004672 ... P49759 31531359
    13 6khd:C (2.7) BS01 3NG 2.7.12.1 GO:0004672 ... P49759 31531359
    14 6khe:A (2.8) BS01 3NG 2.7.12.1 GO:0004672 ... P49760 31531359 BindingDB: IC50=4.0nM
    15 6khf:A (2.598) BS01 3NG 2.7.12.1 GO:0001669 ... P49761 31531359 BindingDB: IC50=41nM
    16 6p5s:A (2.194) BS01 3NG 2.7.11.1 GO:0004672 ... Q9H2X6 31341017
    17 7z1f:A (3.0) BS01 3NG 2.7.11.1
    2.7.11.26    		 GO:0004672 ... P49841 N/A
    18 7z1f:B (3.0) BS01 3NG 2.7.11.1
    2.7.11.26    		 GO:0004672 ... P49841 N/A
    19 7z1g:A (2.85) BS01 3NG 2.7.11.1
    2.7.11.26    		 GO:0004672 ... P49841 N/A
    20 7z5n:A (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    21 7z5n:B (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    22 7z5n:C (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    23 7z5n:D (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    24 7z5n:E (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    25 7z5n:F (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    26 7z5n:G (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    27 7z5n:H (2.77) BS01 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    28 7z5n:H (2.77) BS02 3NG 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 N/A
    29 8qbu:A (1.09) BS02 3NG 2.7.11.1 GO:0000785 ... P19784 N/A
    30 8w4q:A (1.55) BS02 3NG 3.1.4.53 GO:0004114 ... Q08499 37918035
    31 8w4q:B (1.55) BS02 3NG 3.1.4.53 GO:0004114 ... Q08499 37918035
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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