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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    401 1gj6:A (1.5) BS02 132 3.4.21.4 GO:0004175 ... P00760 11731301 MOAD: Ki=0.23uM
    PDBbind: -logKd/Ki=7.00, Ki=0.10uM
    BindingDB: Ki=100nM
    402 1gj7:B (1.5) BS02 132 3.4.21.73 GO:0004252 ... P00749 11731301 MOAD: Ki=0.009uM
    PDBbind: -logKd/Ki=7.89, Ki=0.013uM
    BindingDB: Ki=14nM
    403 1gj9:B (1.8) BS02 134 3.4.21.73 GO:0004252 ... P00749 11731301 MOAD: Ki=0.011uM
    BindingDB: Ki=140nM
    404 1gja:B (1.56) BS02 135 3.4.21.73 GO:0004252 ... P00749 11731301 MOAD: Ki=3.8uM
    PDBbind: -logKd/Ki=5.42, Ki=3.8uM
    BindingDB: Ki=2700nM
    405 1gjd:B (1.75) BS02 136 3.4.21.73 GO:0004252 ... P00749 11731301 MOAD: Ki=6uM
    PDBbind: -logKd/Ki=5.22, Ki=6.0uM
    BindingDB: Ki=6000nM
    406 1gpk:A (2.1) BS01 HUP 3.1.1.7 GO:0001507 ... P04058 12196020 MOAD: Ki=4.3uM
    PDBbind: -logKd/Ki=5.37, Ki=4.3uM
    BindingDB: IC50=11.4nM
    407 1gpn:A (2.35) BS01 HUB 3.1.1.7 GO:0001507 ... P04058 12196020 MOAD: Ki=0.334uM
    PDBbind: -logKd/Ki=6.48, Ki=0.334uM
    BindingDB: Ki=334nM
    408 1gqr:A (2.2) BS01 SAF 3.1.1.7 GO:0001507 ... P04058 11888271 BindingDB: Ki=700nM
    409 1gqs:A (3.0) BS01 SAF 3.1.1.7 GO:0001507 ... P04058 11888271 PDBbind: -logKd/Ki=6.30, Ki=0.5uM
    BindingDB: Ki=700nM
    410 1gr2:A (1.9) BS01 KAI ? GO:0015276 ... P19491 9804426 BindingDB: EC50=380000nM, Ki=3690nM
    411 1gse:A (2.0) BS02 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    412 1gse:B (2.0) BS03 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    413 1gsf:A (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 PDBbind: -logKd/Ki=5.00, IC50~10uM
    BindingDB: IC50=5000nM
    414 1gsf:B (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    415 1gsf:C (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    416 1gsf:D (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-    		 GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    417 1gss:A (2.8) BS01 LEE 2.5.1.18 GO:0000302 ... P09211 1522586 BindingDB: Ki=10000nM, IC50=1.31e+5nM
    418 1gss:B (2.8) BS01 LEE 2.5.1.18 GO:0000302 ... P09211 1522586 BindingDB: Ki=10000nM, IC50=1.31e+5nM
    419 1gu1:A (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    PDBbind: -logKd/Ki=4.52, Ki=30uM
    BindingDB: Kd=30000nM
    420 1gu1:B (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    PDBbind: -logKd/Ki=4.52, Ki=30uM
    BindingDB: Kd=30000nM
    421 1gu1:C (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    422 1gu1:D (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    423 1gu1:E (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    424 1gu1:F (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    425 1gu1:G (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    426 1gu1:H (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    427 1gu1:I (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    428 1gu1:J (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    429 1gu1:K (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    430 1gu1:L (1.8) BS01 FA1 4.2.1.10 GO:0003855 ... P15474 11937054 MOAD: Ki=30uM
    BindingDB: Kd=30000nM
    431 1gw6:A (2.2) BS01 BES 3.3.2.6
    3.4.11.4    		 GO:0003723 ... P09960 11917124 BindingDB: IC50=4000nM, Kd=2050nM, Ki=320nM
    432 1gwq:A (2.45) BS02 ZTW ? N/A P03372 11937504 BindingDB: EC50=1400nM, IC50=1410nM, Ki=4.1nM
    433 1gwq:B (2.45) BS02 ZTW ? N/A P03372 11937504 BindingDB: EC50=1400nM, IC50=1410nM, Ki=4.1nM
    434 1gwr:A (2.4) BS02 EST ? N/A P03372 11937504 BindingDB: IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM
    435 1gwr:B (2.4) BS02 EST ? N/A P03372 11937504 BindingDB: IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM
    436 1gwx:A (2.5) BS01 433 ? GO:0003677 ... Q03181 10198642 BindingDB: EC50=190nM
    437 1gwx:B (2.5) BS01 433 ? GO:0003677 ... Q03181 10198642 BindingDB: EC50=190nM
    438 1gx8:A (2.4) BS01 RTL ? GO:0005515 ... P02754 12054801 PDBbind: -logKd/Ki=6.37, Kd=0.43uM
    BindingDB: Kd=36nM
    439 1h00:A (1.6) BS01 FAP 2.7.11.22 GO:0000082 ... P24941 12941311 MOAD: ic50=38uM
    PDBbind: -logKd/Ki=4.42, IC50=38uM
    BindingDB: IC50=38000nM
    440 1h01:A (1.79) BS01 FAL 2.7.11.22 GO:0000082 ... P24941 12941311 MOAD: ic50=22uM
    PDBbind: -logKd/Ki=4.66, IC50=22uM
    BindingDB: IC50=1000nM
    441 1h07:A (1.85) BS01 MFP 2.7.11.22 GO:0000082 ... P24941 12941311 MOAD: ic50=3uM
    PDBbind: -logKd/Ki=5.52, IC50=3uM
    BindingDB: IC50=3000nM
    442 1h08:A (1.8) BS02 BWP 2.7.11.22 GO:0000082 ... P24941 12941311 BindingDB: IC50=300nM
    443 1h0r:A (2.1) BS01 FA1 4.2.1.10 GO:0003855 ... P9WPX7 N/A MOAD: Ki=200uM
    PDBbind: -logKd/Ki=3.70, Ki=200uM
    BindingDB: Kd=200000nM, Ki=200000nM
    444 1h1p:A (2.1) BS01 CMG 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: Ki=12uM
    PDBbind: -logKd/Ki=4.92, Ki=12uM
    BindingDB: IC50=17000nM
    445 1h1p:C (2.1) BS01 CMG 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: Ki=12uM
    BindingDB: IC50=17000nM
    446 1h1q:A (2.5) BS01 2A6 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1.0uM
    BindingDB: IC50=2300nM
    447 1h1q:C (2.5) BS01 2A6 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: ic50=1uM
    BindingDB: IC50=2300nM
    448 1h1r:A (2.0) BS01 6CP 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: ic50=2.3uM
    PDBbind: -logKd/Ki=5.64, IC50=2.3uM
    BindingDB: IC50=2300nM
    449 1h1r:C (2.0) BS01 6CP 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: ic50=2.3uM
    BindingDB: IC50=2300nM
    450 1h1s:A (2.0) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: Ki=6nM
    PDBbind: -logKd/Ki=8.22, Ki=6nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    451 1h1s:C (2.0) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 12244298 MOAD: Ki=6nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    452 1h22:A (2.15) BS01 E10 3.1.1.7 GO:0001507 ... P04058 12517147 MOAD: Ki=0.8nM
    PDBbind: -logKd/Ki=9.10, Ki=0.8nM
    BindingDB: Ki=0.8nM, IC50=2.4nM
    453 1h23:A (2.15) BS01 E12 3.1.1.7 GO:0001507 ... P04058 12517147 MOAD: Ki=4.5nM
    PDBbind: -logKd/Ki=8.35, Ki=4.5nM
    BindingDB: Ki=4.5nM, IC50=16.0nM
    454 1h2y:A (1.78) BS01 ZPR 3.4.21.26 GO:0004252 ... P23687 12202494 BindingDB: IC50=0.33nM
    455 1h82:A (1.9) BS02 GZZ 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=7.5nM
    BindingDB: Ki=7.5nM
    456 1h82:B (1.9) BS02 GZZ 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=7.5nM
    BindingDB: Ki=7.5nM
    457 1h82:C (1.9) BS02 GZZ 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=7.5nM
    BindingDB: Ki=7.5nM
    458 1h83:A (1.9) BS02 DIA 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=300nM
    BindingDB: Ki=300nM
    459 1h83:B (1.9) BS02 DIA 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=300nM
    BindingDB: Ki=300nM
    460 1h83:C (1.9) BS02 DIA 1.5.3.14
    1.5.3.15    		 GO:0006598 ... O64411 11258887 MOAD: Ki=300nM
    BindingDB: Ki=300nM
    461 1h9u:A (2.7) BS01 LG2 ? GO:0003677 ... P28702 11782480 BindingDB: Ki=75nM
    462 1h9u:B (2.7) BS01 LG2 ? GO:0003677 ... P28702 11782480 BindingDB: Ki=75nM
    463 1h9u:C (2.7) BS01 LG2 ? GO:0003677 ... P28702 11782480 BindingDB: Ki=75nM
    464 1h9u:D (2.7) BS01 LG2 ? GO:0003677 ... P28702 11782480 BindingDB: Ki=75nM
    465 1h9z:A (2.5) BS01 RWF ? GO:0003677 ... P02768 11285262 MOAD: Kd=3.8uM
    PDBbind: -logKd/Ki=5.42, Kd=3.8uM
    BindingDB: Kd=1.2E4nM
    466 1hbj:A (2.5) BS01 FBQ 3.1.1.7 GO:0001507 ... P04058 11563919 PDBbind: -logKd/Ki=8.52, IC50=3.0nM
    BindingDB: IC50=11000nM
    467 1hcb:A (1.6) BS02 BCT 4.2.1.1
    4.2.1.69    		 GO:0004064 ... P00915 8057362 BindingDB: Ki=12000000nM
    468 1hfs:A (1.7) BS06 L04 3.4.24.17 GO:0004222 ... P08254 9083493 MOAD: Ki=2nM
    PDBbind: -logKd/Ki=8.70, Ki=2nM
    BindingDB: Ki=2nM
    469 1hlf:A (2.26) BS02 GL4 2.4.1.1 GO:0000166 ... P00489 11741774 MOAD: Ki=2.3uM
    PDBbind: -logKd/Ki=5.64, Ki=2.3uM
    BindingDB: Ki=5100nM
    470 1hmp:A (2.5) BS01 5GP 2.4.2.8 GO:0000166 ... P00492 8044844 BindingDB: Ki=5800nM
    471 1hmp:B (2.5) BS01 5GP 2.4.2.8 GO:0000166 ... P00492 8044844 BindingDB: Ki=5800nM
    472 1hnn:A (2.4) BS02 SKF 2.1.1.28 GO:0004603 ... P11086 11591352 MOAD: Ki=0.58uM
    PDBbind: -logKd/Ki=6.24, Ki=0.58uM
    BindingDB: Ki=280nM
    473 1hnn:B (2.4) BS02 SKF 2.1.1.28 GO:0004603 ... P11086 11591352 MOAD: Ki=0.58uM
    BindingDB: Ki=280nM
    474 1hov:A (-1.00) BS05 I52 3.4.24.24 GO:0004222 ... P08253 12147339 BindingDB: IC50=<0.100000nM
    475 1hp5:A (2.1) BS01 NGT 3.2.1.52 GO:0004553 ... O85361 11124970 PDBbind: -logKd/Ki=6.55, Ki=280nM
    BindingDB: Ki=20000nM
    476 1hpk:A (-1.00) BS01 ACA 3.4.21.7 N/A P00747 8181476 BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    477 1hqh:A (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 PDBbind: -logKd/Ki=6.30, Ki=0.5uM
    BindingDB: IC50=2000nM
    478 1hqh:B (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 BindingDB: IC50=2000nM
    479 1hqh:C (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 BindingDB: IC50=2000nM
    480 1hs6:A (1.95) BS02 BES 3.3.2.6
    3.4.11.4    		 GO:0003723 ... P09960 11175901 PDBbind: -logKd/Ki=5.38, IC50=4.2uM
    BindingDB: IC50=4000nM, Kd=2050nM, Ki=320nM
    481 1ht5:A (2.75) BS02 FL2 1.14.99.1 GO:0001516 ... P05979 11318639 BindingDB: IC50=210000nM
    482 1ht5:B (2.75) BS02 FL2 1.14.99.1 GO:0001516 ... P05979 11318639 BindingDB: IC50=210000nM
    483 1hut:H (2.9) BS02 0G7 3.4.21.5 GO:0004252 ... P00734 8102368 BindingDB: IC50=1.5nM
    484 1hv5:A (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 PDBbind: -logKd/Ki=8.30, Ki=5nM
    BindingDB: Ki=5nM
    485 1hv5:B (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 BindingDB: Ki=5nM
    486 1hv5:C (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 BindingDB: Ki=5nM
    487 1hv5:D (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 BindingDB: Ki=5nM
    488 1hv5:E (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 BindingDB: Ki=5nM
    489 1hv5:F (2.6) BS04 RXP 3.4.24.- GO:0004222 ... Q02853 11254383 BindingDB: Ki=5nM
    490 1hvy:A (1.9) BS01 D16 2.1.1.45 GO:0000900 ... P04818 11329255 PDBbind: -logKd/Ki=6.54, IC50=0.29uM
    BindingDB: IC50=29000nM
    491 1hvy:B (1.9) BS02 D16 2.1.1.45 GO:0000900 ... P04818 11329255 PDBbind: -logKd/Ki=6.54, IC50=0.29uM
    BindingDB: IC50=29000nM
    492 1hvy:C (1.9) BS01 D16 2.1.1.45 GO:0000900 ... P04818 11329255 BindingDB: IC50=29000nM
    493 1hvy:D (1.9) BS02 D16 2.1.1.45 GO:0000900 ... P04818 11329255 BindingDB: IC50=29000nM
    494 1hwi:A (2.3) BS01 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    495 1hwi:A (2.3) BS03 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    496 1hwi:B (2.3) BS01 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    497 1hwi:B (2.3) BS04 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    498 1hwi:C (2.3) BS01 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    499 1hwi:C (2.3) BS02 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    500 1hwi:D (2.3) BS01 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    501 1hwi:D (2.3) BS03 115 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=28nM
    BindingDB: IC50=28nM
    502 1hwk:A (2.22) BS04 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    503 1hwk:A (2.22) BS05 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    504 1hwk:B (2.22) BS03 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    505 1hwk:B (2.22) BS05 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    506 1hwk:C (2.22) BS01 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    507 1hwk:C (2.22) BS02 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    508 1hwk:D (2.22) BS01 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    509 1hwk:D (2.22) BS03 117 1.1.1.34 GO:0004420 ... P04035 11349148 MOAD: ic50=8nM
    BindingDB: IC50=6nM, Ki=6.2nM
    510 1hww:A (1.87) BS02 SWA 3.2.1.114 GO:0000139 ... Q24451 11406577 MOAD: ic50=20nM
    PDBbind: -logKd/Ki=7.70, IC50=20nM
    BindingDB: IC50=37nM, Ki=3.0nM
    511 1hy7:B (1.5) BS06 MBS 3.4.24.17 GO:0004222 ... P08254 11297453 MOAD: ic50=4090nM
    PDBbind: -logKd/Ki=5.39, IC50=4.09uM
    BindingDB: IC50=4090nM
    512 1i00:A (2.5) BS02 D16 2.1.1.45 GO:0000900 ... P04818 11316879 MOAD: Ki=0.46uM
    PDBbind: -logKd/Ki=6.34, Ki=0.46uM
    BindingDB: IC50=29000nM
    513 1i00:B (2.5) BS03 D16 2.1.1.45 GO:0000900 ... P04818 11316879 MOAD: Ki=0.46uM
    PDBbind: -logKd/Ki=6.34, Ki=0.46uM
    BindingDB: IC50=29000nM
    514 1i2z:A (2.8) BS02 654 1.3.1.9 GO:0004318 ... P0AEK4 11514139 BindingDB: IC50=13700nM
    515 1i2z:B (2.8) BS02 654 1.3.1.9 GO:0004318 ... P0AEK4 11514139 BindingDB: IC50=13700nM
    516 1i30:A (2.4) BS02 826 1.3.1.9 GO:0004318 ... P0AEK4 11527706 BindingDB: IC50=4200nM
    517 1i30:B (2.4) BS02 826 1.3.1.9 GO:0004318 ... P0AEK4 11527706 BindingDB: IC50=4200nM
    518 1i37:A (2.0) BS01 DHT ? N/A P15207 11320241 PDBbind: -logKd/Ki=9.57, Ki=0.27nM
    BindingDB: IC50=3.1nM, EC50=0.97nM, Ki=0.43nM
    519 1i38:A (2.0) BS01 DHT ? N/A P15207 11320241 BindingDB: IC50=3.1nM, EC50=0.97nM, Ki=0.43nM
    520 1i5r:A (1.6) BS01 HYC 1.1.1.51
    1.1.1.62    		 GO:0003824 ... P14061 12223444 MOAD: Ki=3nM
    PDBbind: -logKd/Ki=8.52, Ki=3.0nM
    BindingDB: IC50=52nM, Ki=3nM
    521 1i72:A (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    522 1i72:B (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    523 1i7g:A (2.2) BS01 AZ2 ? GO:0003677 ... Q07869 11587644 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1.0uM
    BindingDB: EC50=820nM, Ki=1000nM
    524 1i7i:A (2.35) BS01 AZ2 ? GO:0003677 ... P37231 11587644 PDBbind: -logKd/Ki=6.70, IC50=0.2uM
    BindingDB: EC50=704nM, Ki=18nM
    525 1i7i:B (2.35) BS01 AZ2 ? GO:0003677 ... P37231 11587644 BindingDB: EC50=704nM, Ki=18nM
    526 1i8z:A (1.93) BS02 INL 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 11831900 MOAD: ic50=1.27nM
    PDBbind: -logKd/Ki=8.90, IC50=1.27nM
    BindingDB: Ki=0.15nM, IC50=1.3nM
    527 1i91:A (2.0) BS02 INQ 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 11831900 MOAD: ic50=1.15nM
    PDBbind: -logKd/Ki=8.94, IC50=1.15nM
    BindingDB: Ki=0.15nM, IC50=1.2nM
    528 1i9o:A (1.86) BS02 IOC 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 11572683 MOAD: Kd=3.8nM
    PDBbind: -logKd/Ki=8.42, Kd=3.8nM
    BindingDB: Kd=2.3nM
    529 1i9o:A (1.86) BS03 IOC 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 11572683 MOAD: Kd=3.8nM
    PDBbind: -logKd/Ki=8.42, Kd=3.8nM
    BindingDB: Kd=2.3nM
    530 1ia1:A (1.7) BS02 TQ3 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.034uM
    BindingDB: IC50=34nM
    531 1ia1:B (1.7) BS02 TQ3 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.034uM
    BindingDB: IC50=34nM
    532 1ia2:A (1.82) BS02 TQ4 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.023uM
    BindingDB: IC50=23nM
    533 1ia2:B (1.82) BS02 TQ4 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.023uM
    BindingDB: IC50=23nM
    534 1ia3:A (1.78) BS02 TQ5 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=8nM
    BindingDB: IC50=8nM
    535 1ia3:B (1.78) BS02 TQ5 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=8nM
    BindingDB: IC50=8nM
    536 1ia4:A (1.85) BS02 TQ6 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM
    537 1ia4:B (1.85) BS02 TQ6 1.5.1.3 GO:0004146 ... P22906 11520201 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM
    538 1ict:A (3.0) BS01 T44 ? GO:0005179 ... P02766 11418763 BindingDB: IC50=10500nM
    539 1ict:B (3.0) BS01 T44 ? GO:0005179 ... P02766 11418763 BindingDB: IC50=10500nM
    540 1ict:C (3.0) BS01 T44 ? GO:0005179 ... P02766 11418763 BindingDB: IC50=10500nM
    541 1ict:D (3.0) BS01 T44 ? GO:0005179 ... P02766 11418763 BindingDB: IC50=10500nM
    542 1ie9:A (1.4) BS01 VDX ? GO:0003677 ... P11473 11344298 PDBbind: -logKd/Ki=10.19, Kd=0.065nM
    BindingDB: EC50=10nM, IC50=1.1nM, Kd=0.065nM
    543 1iei:A (2.5) BS02 ZES 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 11914486 MOAD: ic50=44nM
    BindingDB: IC50=8nM
    544 1iep:A (2.1) BS01 STI 2.7.10.2 GO:0004672 ... P00520 12154025 MOAD: ic50=100nM
    PDBbind: -logKd/Ki=7.00, IC50=100nM
    BindingDB: IC50=10.8nM
    545 1iep:B (2.1) BS01 STI 2.7.10.2 GO:0004672 ... P00520 12154025 MOAD: ic50=100nM
    BindingDB: IC50=10.8nM
    546 1if4:A (1.93) BS02 FBS 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 N/A BindingDB: Kd=435nM, IC50=203nM
    547 1il4:A (2.6) BS01 9DG 3.2.2.22 GO:0017148 ... P02879 11754581 PDBbind: -logKd/Ki=2.85, IC50=1.4mM
    BindingDB: IC50=1400000nM
    548 1il9:A (3.1) BS01 MOG 3.2.2.22 GO:0017148 ... P02879 11754581 PDBbind: -logKd/Ki=3.40, IC50=0.40mM
    BindingDB: IC50=400000nM
    549 1ilh:A (2.76) BS01 SRL ? GO:0003677 ... O75469 11408620 PDBbind: -logKd/Ki=7.39, Kd=41nM
    BindingDB: EC50=440nM
    550 1ipc:A (2.0) BS01 MGP ? GO:0000082 ... P06730 11879179 BindingDB: Ki=28nM
    551 1iss:A (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    552 1iss:B (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    553 1iwo:A (3.1) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 12167852 BindingDB: Kd=0.200000nM, IC50=0.2nM
    554 1iwo:B (3.1) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 12167852 BindingDB: Kd=0.200000nM, IC50=0.2nM
    555 1iyk:A (2.3) BS02 MIM 2.3.1.97 GO:0004379 ... P30418 12401496 MOAD: Ki=0.25uM
    BindingDB: Ki=31nM
    556 1iyk:B (2.3) BS02 MIM 2.3.1.97 GO:0004379 ... P30418 12401496 MOAD: Ki=0.25uM
    BindingDB: Ki=31nM
    557 1iyl:A (3.2) BS01 R64 2.3.1.97 GO:0004379 ... P30418 12401496 PDBbind: -logKd/Ki=9.00, IC50=1nM
    BindingDB: IC50=1nM
    558 1iyl:B (3.2) BS01 R64 2.3.1.97 GO:0004379 ... P30418 12401496 BindingDB: IC50=1nM
    559 1iyl:C (3.2) BS01 R64 2.3.1.97 GO:0004379 ... P30418 12401496 BindingDB: IC50=1nM
    560 1j3i:A (2.33) BS01 WRA 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=0.011nM
    BindingDB: IC50=0.570000nM, Ki=0.5nM
    561 1j3i:B (2.33) BS01 WRA 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=0.011nM
    BindingDB: IC50=0.570000nM, Ki=0.5nM
    562 1j3j:A (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=9.8nM
    BindingDB: Ki=0.6nM, IC50=30900nM
    563 1j3j:B (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=9.8nM
    BindingDB: Ki=0.6nM, IC50=30900nM
    564 1j3k:A (2.1) BS01 WRA 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=0.037nM
    BindingDB: IC50=0.570000nM, Ki=0.5nM
    565 1j3k:B (2.1) BS01 WRA 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=0.037nM
    BindingDB: IC50=0.570000nM, Ki=0.5nM
    566 1jaq:A (2.4) BS02 01S 3.4.24.34 GO:0004222 ... P22894 7737183 MOAD: Ki=33uM
    PDBbind: -logKd/Ki=4.48, Ki=33uM
    BindingDB: Ki=121000nM
    567 1jcq:A (2.3) BS02 FPP 2.5.1.58
    2.5.1.59    		 GO:0004659 ... P49354 11687658 BindingDB: Kd=2.0nM
    568 1jd0:A (1.5) BS02 AZM 4.2.1.1 GO:0004089 ... O43570 11493685 PDBbind: -logKd/Ki=8.24, Ki=5.7nM
    BindingDB: Ki=5.7nM, Kd=130nM, IC50=60nM
    569 1jd0:B (1.5) BS02 AZM 4.2.1.1 GO:0004089 ... O43570 11493685 BindingDB: Ki=5.7nM, Kd=130nM, IC50=60nM
    570 1jg0:A (2.0) BS02 DDT 2.1.1.45 GO:0000287 ... P0A884 11590022 MOAD: ic50=5uM
    PDBbind: -logKd/Ki=5.30, IC50=5.0uM
    BindingDB: IC50=5.0e+3nM, Ki=1.8e+3nM
    571 1jg0:B (2.0) BS02 DDT 2.1.1.45 GO:0000287 ... P0A884 11590022 MOAD: ic50=5uM
    PDBbind: -logKd/Ki=5.30, IC50=5.0uM
    BindingDB: IC50=5.0e+3nM, Ki=1.8e+3nM
    572 1jj9:A (2.0) BS05 BBT 3.4.24.34 GO:0004222 ... P22894 11278347 MOAD: ic50=1700nM
    PDBbind: -logKd/Ki=5.77, IC50=1.7uM
    BindingDB: IC50=1700nM
    573 1jk7:A (1.9) BS03 OKA 3.1.3.16 GO:0000070 ... P36873 11535607 PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=>5000nM
    574 1jkh:A (2.5) BS01 EFZ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0003676 ... P04585 11575933 BindingDB: IC50=25nM, Ki=30nM
    575 1jpz:A (1.65) BS02 140 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 11695892 MOAD: Kd=262nM
    BindingDB: Kd=82nM
    576 1jpz:B (1.65) BS02 140 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 11695892 MOAD: Kd=262nM
    BindingDB: Kd=82nM
    577 1jqd:A (2.28) BS01 SAH 2.1.1.8 GO:0001692 ... P50135 11566133 MOAD: Ki=6.9uM
    PDBbind: -logKd/Ki=5.16, Ki=6.9uM
    BindingDB: Ki=18100nM
    578 1jqd:B (2.28) BS01 SAH 2.1.1.8 GO:0001692 ... P50135 11566133 MOAD: Ki=6.9uM
    BindingDB: Ki=18100nM
    579 1jqe:A (1.91) BS01 SAH 2.1.1.8 GO:0001692 ... P50135 11566133 BindingDB: Ki=18100nM
    580 1jqe:B (1.91) BS01 SAH 2.1.1.8 GO:0001692 ... P50135 11566133 BindingDB: Ki=18100nM
    581 1jsv:A (1.96) BS01 U55 2.7.11.22 GO:0000082 ... P24941 11604388 PDBbind: -logKd/Ki=5.70, Ki=2uM
    BindingDB: IC50=1900nM
    582 1ju6:A (2.89) BS02 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    583 1ju6:B (2.89) BS03 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    584 1ju6:C (2.89) BS02 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    585 1ju6:D (2.89) BS03 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    586 1juj:A (3.0) BS02 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 PDBbind: -logKd/Ki=6.96, Ki=109nM
    BindingDB: IC50=9500nM, Ki=1.3nM
    587 1juj:B (3.0) BS03 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 PDBbind: -logKd/Ki=6.96, Ki=109nM
    BindingDB: IC50=9500nM, Ki=1.3nM
    588 1juj:C (3.0) BS02 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    589 1juj:D (3.0) BS03 LYA 2.1.1.45 GO:0000900 ... P04818 11697906 BindingDB: IC50=9500nM, Ki=1.3nM
    590 1jvu:A (1.78) BS01 C2P 4.6.1.18 GO:0003676 ... P61823 11746706 PDBbind: -logKd/Ki=5.15, Ki=7uM
    BindingDB: Ki=7000nM
    591 1jyx:A (1.75) BS06 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    592 1jyx:A (1.75) BS07 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    593 1jyx:B (1.75) BS07 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    594 1jyx:C (1.75) BS07 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    595 1jyx:D (1.75) BS06 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    596 1jyx:D (1.75) BS07 IPT 3.2.1.23 GO:0000287 ... P00722 11732897 BindingDB: Ki=7.6e+4nM
    597 1k06:A (1.8) BS01 BZD 2.4.1.1 GO:0000166 ... P00489 11895439 MOAD: Ki=4.6uM
    PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    598 1k06:A (1.8) BS02 BZD 2.4.1.1 GO:0000166 ... P00489 11895439 MOAD: Ki=4.6uM
    PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    599 1k08:A (2.26) BS01 BZD 2.4.1.1 GO:0000166 ... P00489 11895439 MOAD: Ki=4.6uM
    PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    600 1k08:A (2.26) BS02 BZD 2.4.1.1 GO:0000166 ... P00489 11895439 MOAD: Ki=4.6uM
    PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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