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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 10gs:A (2.2) BS01 VWW 2.5.1.18 GO:0000302 ... P09211 9398518 MOAD: Ki=0.4uM
    PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    BindingDB: Ki=420nM
    2 10gs:B (2.2) BS01 VWW 2.5.1.18 GO:0000302 ... P09211 9398518 MOAD: Ki=0.4uM
    PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    BindingDB: Ki=420nM
    3 11gs:A (2.3) BS02 EAA 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    BindingDB: IC50=2.6e+4nM
    4 11gs:B (2.3) BS02 EAA 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    BindingDB: IC50=2.6e+4nM
    5 187l:A (1.8) BS01 PXY 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Kd=422uM
    PDBbind: -logKd/Ki=3.37, Kd=422uM
    BindingDB: Kd=151000nM
    6 1a28:A (1.8) BS01 STR ? N/A P06401 9620806 MOAD: Ki=5.1nM
    PDBbind: -logKd/Ki=8.29, Ki=5.1nM
    BindingDB: Ki=3.5nM, EC50=2.9nM, IC50=>10000nM
    7 1a28:B (1.8) BS01 STR ? N/A P06401 9620806 MOAD: Ki=5.1nM
    BindingDB: Ki=3.5nM, EC50=2.9nM, IC50=>10000nM
    8 1a29:A (2.74) BS05 TFP ? GO:0000922 ... P62157 9799490 BindingDB: Kd=5000nM
    9 1a29:A (2.74) BS06 TFP ? GO:0000922 ... P62157 9799490 BindingDB: Kd=5000nM
    10 1a52:A (2.8) BS01 EST ? N/A P03372 9600906 PDBbind: -logKd/Ki=9.86, Ki=0.138nM
    BindingDB: IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM
    11 1a52:B (2.8) BS01 EST ? N/A P03372 9600906 BindingDB: IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM
    12 1a85:A (2.0) BS05 0DY 3.4.24.34 GO:0004222 ... P22894 9655333 PDBbind: -logKd/Ki=4.52, IC50=30uM
    BindingDB: Ki=26000nM
    13 1a86:A (2.0) BS01 0ZB 3.4.24.34 GO:0004222 ... P22894 9655333 PDBbind: -logKd/Ki=4.00, IC50=101uM
    BindingDB: Ki=88000nM
    14 1a8i:A (1.78) BS01 GLS 2.4.1.1 GO:0000166 ... P00489 9568898 MOAD: Ki=3uM
    PDBbind: -logKd/Ki=5.52, Ki=3.0uM
    BindingDB: Ki=3100nM, IC50=3100nM
    15 1a9q:A (2.0) BS01 HPA 2.4.2.1 GO:0003824 ... P55859 9585525 PDBbind: -logKd/Ki=6.17, Kd=0.68uM
    BindingDB: Kd=680nM
    16 1a9r:A (2.0) BS01 HPA 2.4.2.1 GO:0003824 ... P55859 9585525 BindingDB: Kd=680nM
    17 1a9t:A (2.0) BS02 HPA 2.4.2.1 GO:0003824 ... P55859 9585525 BindingDB: Kd=680nM
    18 1acj:A (2.8) BS01 THA 3.1.1.7 GO:0001507 ... P04058 8415649 PDBbind: -logKd/Ki=8.09, IC50=8.2nM
    BindingDB: IC50=29nM, Ki=40nM
    19 1ah0:A (2.3) BS02 SBI 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P80276 9195881 BindingDB: IC50=1100nM
    20 1ah3:A (2.3) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P80276 9195881 BindingDB: IC50=16nM
    21 1aj6:A (2.3) BS01 NOV 5.6.2.2 GO:0003677 ... P0AES6 9245398 MOAD: Kd=1.2uM
    PDBbind: -logKd/Ki=5.92, Kd=1.2uM
    BindingDB: IC50=170nM, Kd=7.0nM, Ki=7.0nM
    22 1ao8:A (-1.00) BS01 MTX 1.5.1.3 GO:0004146 ... P00381 9514736 PDBbind: -logKd/Ki=8.22, IC50=6nM
    BindingDB: IC50=16nM, Ki=0.004000nM
    23 1aoe:A (1.6) BS02 GW3 1.5.1.3 GO:0004146 ... P22906 9374515 MOAD: Ki=0.22nM
    BindingDB: IC50=4nM, Ki=0.22nM
    24 1aoe:B (1.6) BS02 GW3 1.5.1.3 GO:0004146 ... P22906 9374515 MOAD: Ki=0.22nM
    BindingDB: IC50=4nM, Ki=0.22nM
    25 1apz:B (2.3) BS01 ASP 3.5.1.26 GO:0016787 ... P20933 8846222 BindingDB: Ki=600000nM
    26 1apz:D (2.3) BS01 ASP 3.5.1.26 GO:0016787 ... P20933 8846222 BindingDB: Ki=600000nM
    27 1au0:A (2.6) BS01 SDK 3.4.22.38 GO:0006508 ... P43235 N/A PDBbind: -logKd/Ki=7.66, Ki=22nM
    BindingDB: Ki=22nM
    28 1avn:A (2.0) BS02 AZI 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9265618 BindingDB: Ki=1500000nM
    29 1axw:A (1.7) BS02 MTX 2.1.1.45 GO:0000287 ... P0A884 N/A BindingDB: IC50=90000nM
    30 1axw:B (1.7) BS03 MTX 2.1.1.45 GO:0000287 ... P0A884 N/A BindingDB: IC50=90000nM
    31 1ayu:A (2.2) BS01 INA 3.4.22.38 GO:0006508 ... P43235 9405598 PDBbind: -logKd/Ki=9.15, Ki=0.7nM
    BindingDB: Ki=0.7nM
    32 1ayv:A (2.3) BS01 IN6 3.4.22.38 GO:0006508 ... P43235 9405598 PDBbind: -logKd/Ki=8.00, Ki=10nM
    BindingDB: Ki=10.0nM
    33 1ayw:A (2.4) BS01 IN3 3.4.22.38 GO:0006508 ... P43235 9405598 BindingDB: Ki=27nM
    34 1az1:A (1.8) BS02 ALR 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 9405046 BindingDB: IC50=79000nM, Ki=2000nM
    35 1az1:A (1.8) BS03 ALR 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 9405046 BindingDB: IC50=79000nM, Ki=2000nM
    36 1azm:A (2.0) BS02 AZM 4.2.1.1
    4.2.1.69    		 GO:0004064 ... P00915 7932756 PDBbind: -logKd/Ki=6.10, Ki=0.8uM
    BindingDB: Ki=250nM, Kd=1400nM, IC50=5.8nM
    37 1b0f:A (3.0) BS02 SEI 3.4.21.37 GO:0000122 ... P08246 9651152 PDBbind: -logKd/Ki=7.70, Ki=20nM
    BindingDB: Ki=25nM
    38 1b2i:A (-1.00) BS01 AMH 3.4.21.7 N/A P00747 10625440 PDBbind: -logKd/Ki=5.51, IC50=3.1uM
    BindingDB: Kd=1100nM, IC50=3100nM, Ki=25000000nM
    39 1b3d:B (2.3) BS06 S27 3.4.24.17 GO:0004222 ... P08254 10543949 BindingDB: IC50=24nM
    40 1b4d:A (2.0) BS01 CRA 2.4.1.1 GO:0000166 ... P00489 10211820 MOAD: Ki=15.6uM
    PDBbind: -logKd/Ki=4.81, Ki=15.6uM
    BindingDB: Ki=16000nM
    41 1b4e:A (2.0) BS03 SHF 4.2.1.24 GO:0000287 ... P0ACB2 10194344 BindingDB: Ki=2.200e+6nM
    42 1b6a:A (1.6) BS03 TN4 3.4.11.18 GO:0003723 ... P50579 9812898 BindingDB: IC50=1nM, Ki=1nM
    43 1b8n:A (2.0) BS01 IMG 2.4.2.1 GO:0003824 ... P55859 12463747 MOAD: Ki=30pM
    PDBbind: -logKd/Ki=10.52, Ki=30pM
    BindingDB: Ki=0.030000nM
    44 1b9s:A (2.5) BS02 FDI 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50>667uM
    PDBbind: -logKd/Ki=3.18, IC50>667uM
    BindingDB: IC50=670000nM
    45 1b9t:A (2.4) BS02 RAI 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50=8uM
    PDBbind: -logKd/Ki=5.10, IC50=8uM
    BindingDB: IC50=8000nM
    46 1b9v:A (2.35) BS02 RA2 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50=224uM
    PDBbind: -logKd/Ki=3.65, IC50=224uM
    BindingDB: IC50=271000nM
    47 1bb0:B (2.1) BS03 0IV 3.4.21.5 GO:0004252 ... P00734 9724521 PDBbind: -logKd/Ki=8.36, Ki=4.4nM
    BindingDB: IC50=28.8nM
    48 1bcd:A (1.9) BS02 FMS 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8070585 MOAD: Kd=2nM
    PDBbind: -logKd/Ki=8.70, Ki=2nM
    BindingDB: Kd=130nM, IC50=13nM
    49 1bcu:H (2.0) BS03 PRL 3.4.21.5 GO:0004252 ... P00734 9559654 MOAD: Kd=0.53mM
    PDBbind: -logKd/Ki=3.28, Kd=0.53mM
    BindingDB: IC50=12000nM
    50 1bgq:A (2.5) BS01 RDC ? GO:0005524 ... P02829 9925731 MOAD: Kd=2.7nM
    PDBbind: -logKd/Ki=8.57, Kd=2.7nM
    BindingDB: IC50=2e+2nM
    51 1bhx:B (2.3) BS02 R56 3.4.21.5 GO:0004252 ... P00734 9733491 PDBbind: -logKd/Ki=6.84, Ki=0.145uM
    BindingDB: Ki=145nM
    52 1bhx:F (2.3) BS01 R56 3.4.21.5 GO:0004252 ... P00734 9733491 MOAD: Ki=0.145uM
    PDBbind: -logKd/Ki=6.84, Ki=0.145uM
    BindingDB: Ki=145nM
    53 1bic:A (1.9) BS02 BCT 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8451242 BindingDB: Ki=85000000nM
    54 1biw:B (2.5) BS06 S80 3.4.24.17 GO:0004222 ... P08254 9873489 MOAD: ic50=104nM
    PDBbind: -logKd/Ki=6.98, IC50=104nM
    BindingDB: IC50=104nM
    55 1bkf:A (1.6) BS01 FK5 5.2.1.8 GO:0000413 ... P62942 N/A MOAD: Ki=2.1nM
    BindingDB: Kd=0.200000nM, EC50=0.900000nM, Ki=0.40nM, IC50=2.3nM
    56 1bl4:A (1.9) BS01 AP1 5.2.1.8 GO:0000413 ... P62942 9724721 MOAD: ic50=1.8nM
    PDBbind: -logKd/Ki=8.74, IC50=1.8nM
    BindingDB: IC50=8.2nM
    57 1bl4:B (1.9) BS01 AP1 5.2.1.8 GO:0000413 ... P62942 9724721 MOAD: ic50=1.8nM
    PDBbind: -logKd/Ki=8.74, IC50=1.8nM
    BindingDB: IC50=8.2nM
    58 1bl6:A (2.5) BS01 SB6 2.7.11.24 GO:0000077 ... Q16539 9753691 PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    BindingDB: IC50=160nM
    59 1bl7:A (2.5) BS01 SB4 2.7.11.24 GO:0000077 ... Q16539 9753691 PDBbind: -logKd/Ki=7.72, IC50=0.019uM
    BindingDB: IC50=19nM
    60 1bm7:A (2.0) BS01 FLF ? GO:0005179 ... P02766 9789022 MOAD: Kd=30nM
    PDBbind: -logKd/Ki=7.52, Kd=30nM
    BindingDB: IC50=2900nM
    61 1bm7:B (2.0) BS01 FLF ? GO:0005179 ... P02766 9789022 MOAD: Kd=30nM
    PDBbind: -logKd/Ki=7.52, Kd=30nM
    BindingDB: IC50=2900nM
    62 1bmk:A (2.4) BS01 SB5 2.7.11.24 GO:0000077 ... Q16539 9753691 PDBbind: -logKd/Ki=7.60, IC50=0.025uM
    BindingDB: IC50=25nM
    63 1bmm:H (2.6) BS03 BM2 3.4.21.5 GO:0004252 ... P00734 8745399 PDBbind: -logKd/Ki=7.10, Ki=79nM
    BindingDB: IC50=390nM
    64 1bmn:H (2.8) BS03 BM9 3.4.21.5 GO:0004252 ... P00734 8745399 PDBbind: -logKd/Ki=8.44, Ki=3.6nM
    BindingDB: IC50=16nM, Ki=3.6nM
    65 1bn1:A (2.1) BS02 AL5 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.46nM
    PDBbind: -logKd/Ki=9.34, Kd=0.46nM
    BindingDB: Kd=0.46nM
    66 1bn3:A (2.2) BS02 AL6 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.13nM
    PDBbind: -logKd/Ki=9.89, Kd=0.13nM
    BindingDB: Kd=0.13nM
    67 1bn4:A (2.1) BS02 AL9 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.49nM
    PDBbind: -logKd/Ki=9.31, Kd=0.49nM
    BindingDB: Kd=0.49nM
    68 1bnm:A (2.6) BS02 AL8 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 PDBbind: -logKd/Ki=10.00, Kd=0.10nM
    BindingDB: Kd=0.1nM
    69 1bnn:A (2.3) BS02 AL1 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.1nM
    PDBbind: -logKd/Ki=10.00, Kd=0.10nM
    BindingDB: Kd=0.1nM
    70 1bnq:A (2.4) BS02 AL4 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.32nM
    PDBbind: -logKd/Ki=9.49, Kd=0.32nM
    BindingDB: Kd=0.32nM
    71 1bnt:A (2.15) BS02 AL2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.16nM
    PDBbind: -logKd/Ki=9.80, Kd=0.16nM
    BindingDB: Kd=0.16nM
    72 1bnu:A (2.15) BS02 AL3 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.2nM
    PDBbind: -logKd/Ki=9.70, Kd=0.20nM
    BindingDB: Kd=0.2nM
    73 1bnv:A (2.4) BS02 AL7 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=1.7nM
    PDBbind: -logKd/Ki=8.77, Kd=1.70nM
    BindingDB: Kd=1.7nM
    74 1bnw:A (2.25) BS02 TPD 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9865942 MOAD: Kd=0.83nM
    PDBbind: -logKd/Ki=9.08, Kd=0.83nM
    BindingDB: Kd=0.83nM
    75 1boz:A (2.1) BS02 PRD 1.5.1.3 GO:0000900 ... P00374 9719595 MOAD: ic50=8500nM
    BindingDB: IC50=28nM
    76 1bqo:B (2.3) BS06 N25 3.4.24.17 GO:0004222 ... P08254 9733482 MOAD: ic50=18.4nM
    PDBbind: -logKd/Ki=7.74, IC50=18.4nM
    BindingDB: IC50=18nM, Ki=18nM
    77 1bzj:A (2.25) BS01 PIC 3.1.3.48 GO:0004725 ... P18031 9922143 MOAD: Ki=22uM
    PDBbind: -logKd/Ki=4.66, Ki=22uM
    BindingDB: Ki=22000nM
    78 1bzm:A (2.0) BS02 MZM 4.2.1.1
    4.2.1.69    		 GO:0004064 ... P00915 7932756 BindingDB: Ki=50nM, IC50=68nM
    79 1bzy:A (2.0) BS01 IMU 2.4.2.8 GO:0000166 ... P00492 10360366 MOAD: Kd=4.6nM
    PDBbind: -logKd/Ki=8.34, Kd=4.6nM
    BindingDB: Ki=4.6nM
    80 1bzy:B (2.0) BS01 IMU 2.4.2.8 GO:0000166 ... P00492 10360366 MOAD: Kd=4.6nM
    BindingDB: Ki=4.6nM
    81 1bzy:C (2.0) BS01 IMU 2.4.2.8 GO:0000166 ... P00492 10360366 MOAD: Kd=4.6nM
    BindingDB: Ki=4.6nM
    82 1bzy:D (2.0) BS01 IMU 2.4.2.8 GO:0000166 ... P00492 10360366 MOAD: Kd=4.6nM
    BindingDB: Ki=4.6nM
    83 1c14:A (2.0) BS02 TCL 1.3.1.9 GO:0004318 ... P0AEK4 10595560 MOAD: ic50=120nM
    BindingDB: IC50=430nM
    84 1c14:B (2.0) BS02 TCL 1.3.1.9 GO:0004318 ... P0AEK4 10595560 MOAD: ic50=120nM
    BindingDB: IC50=430nM
    85 1c3b:A (2.25) BS01 BZB 3.5.2.6 GO:0008800 ... P00811 10595535 PDBbind: -logKd/Ki=7.57, Ki=27nM
    BindingDB: IC50=200nM, Ki=27nM
    86 1c3b:B (2.25) BS01 BZB 3.5.2.6 GO:0008800 ... P00811 10595535 BindingDB: IC50=200nM, Ki=27nM
    87 1c5n:H (1.5) BS03 ESI 3.4.21.5 GO:0004252 ... P00734 10779411 MOAD: Ki=20uM
    PDBbind: -logKd/Ki=4.70, Ki=20uM
    BindingDB: Ki=20000nM
    88 1c5q:A (1.43) BS02 ESI 3.4.21.4 GO:0004175 ... P00760 10779411 MOAD: Ki=0.44uM
    PDBbind: -logKd/Ki=6.36, Ki=0.44uM
    BindingDB: Ki=440nM
    89 1c5r:A (1.47) BS02 ESI 3.4.21.4 GO:0004175 ... P00760 10779411 BindingDB: Ki=440nM
    90 1c5s:A (1.36) BS02 ESX 3.4.21.4 GO:0004175 ... P00760 10779411 MOAD: Ki=1uM
    PDBbind: -logKd/Ki=6.00, Ki=1.0uM
    BindingDB: Ki=1000nM
    91 1c5t:A (1.37) BS02 ESP 3.4.21.4 GO:0004175 ... P00760 10779411 MOAD: Ki=80uM
    PDBbind: -logKd/Ki=4.10, Ki=80uM
    BindingDB: Ki=80000nM
    92 1c5u:A (1.37) BS03 ESP 3.4.21.4 GO:0004175 ... P00760 10779411 BindingDB: Ki=80000nM
    93 1c5w:B (1.94) BS02 ESI 3.4.21.73 GO:0004252 ... P00749 10779411 BindingDB: Ki=210nM
    94 1c5x:B (1.75) BS02 ESI 3.4.21.73 GO:0004252 ... P00749 10779411 MOAD: Ki=0.21uM
    PDBbind: -logKd/Ki=6.68, Ki=0.21uM
    BindingDB: Ki=210nM
    95 1c5y:B (1.65) BS02 ESP 3.4.21.73 GO:0004252 ... P00749 10779411 MOAD: Ki=63uM
    PDBbind: -logKd/Ki=4.20, Ki=63uM
    BindingDB: Ki=63000nM
    96 1c83:A (1.8) BS01 OAI 3.1.3.48 GO:0004725 ... P18031 10702277 MOAD: Ki=14uM
    PDBbind: -logKd/Ki=4.85, Ki=14uM
    BindingDB: Ki=7943.28nM
    97 1c84:A (2.35) BS01 761 3.1.3.48 GO:0004725 ... P18031 10702277 MOAD: Ki=9.9uM
    PDBbind: -logKd/Ki=5.00, Ki=9.9uM
    BindingDB: Ki=10000nM
    98 1c85:A (2.72) BS01 OBA 3.1.3.48 GO:0004725 ... P18031 10702277 PDBbind: -logKd/Ki=4.64, Ki=23uM
    BindingDB: Ki=22908.68nM
    99 1c86:A (2.3) BS01 OPA 3.1.3.48 GO:0004725 ... P18031 10744717 MOAD: Ki=20uM
    PDBbind: -logKd/Ki=4.70, Ki=20uM
    BindingDB: Ki=71449632607551nM
    100 1c87:A (2.1) BS01 OPA 3.1.3.48 GO:0004725 ... P18031 10744717 MOAD: Ki=63uM
    PDBbind: -logKd/Ki=4.20, Ki=63uM
    BindingDB: Ki=71449632607551nM
    101 1c88:A (1.8) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 10744717 MOAD: Ki=5.1uM
    PDBbind: -logKd/Ki=5.29, Ki=5.1uM
    BindingDB: IC50=500000nM, Ki=11500nM
    102 1c8k:A (1.76) BS02 CPB 2.4.1.1 GO:0000166 ... P00489 10924512 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1uM
    BindingDB: IC50=1200nM
    103 1c8l:A (2.3) BS03 CFF 2.4.1.1 GO:0000166 ... P00489 11368311 MOAD: ic50=0.45mM
    BindingDB: IC50=114000nM
    104 1c9h:A (2.0) BS01 RAP 5.2.1.8 GO:0002027 ... P68106 10713512 BindingDB: Kd=0.200000nM
    105 1ca8:B (2.1) BS03 0KV 3.4.21.5 GO:0004252 ... P00734 9724521 PDBbind: -logKd/Ki=9.49, Ki=0.32nM
    BindingDB: IC50=0.67nM
    106 1cah:A (1.88) BS02 BCT 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 1474587 BindingDB: Ki=85000000nM
    107 1cam:A (1.7) BS02 BCT 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 7901850 BindingDB: Ki=85000000nM
    108 1can:A (1.9) BS01 NO3 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 1336460 BindingDB: Ki=35000000nM
    109 1cbr:A (2.9) BS01 REA ? GO:0005501 ... P62965 7704533 PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=>200nM
    110 1cbr:B (2.9) BS01 REA ? GO:0005501 ... P62965 7704533 PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=>200nM
    111 1cbx:A (2.0) BS02 BZS 3.4.17.1 GO:0004181 ... P00730 1738164 MOAD: Ki=0.45uM
    PDBbind: -logKd/Ki=6.35, Ki=0.45uM
    BindingDB: Ki=500nM
    112 1cea:A (2.06) BS01 ACA 3.4.21.7 N/A P00747 8611560 MOAD: Kd~11uM
    PDBbind: -logKd/Ki=4.96, Kd=11uM
    BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    113 1cea:B (2.06) BS01 ACA 3.4.21.7 N/A P00747 8611560 MOAD: Kd~11uM
    PDBbind: -logKd/Ki=4.96, Kd=11uM
    BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    114 1ceb:A (2.07) BS01 AMH 3.4.21.7 N/A P00747 8611560 MOAD: Kd~1uM
    PDBbind: -logKd/Ki=6.00, Kd=1uM
    BindingDB: Kd=1100nM, IC50=3100nM, Ki=25000000nM
    115 1ceb:B (2.07) BS01 AMH 3.4.21.7 N/A P00747 8611560 MOAD: Kd~1uM
    BindingDB: Kd=1100nM, IC50=3100nM, Ki=25000000nM
    116 1cil:A (1.6) BS02 ETS 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8142888 MOAD: Ki=0.372nM
    PDBbind: -logKd/Ki=9.43, Ki=0.37nM
    BindingDB: Ki=9nM, IC50=26.61nM, Kd=0.043000nM
    117 1cim:A (2.1) BS02 PTS 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8142888 MOAD: Ki=1.52nM
    PDBbind: -logKd/Ki=8.82, Ki=1.52nM
    BindingDB: Ki=1.5nM
    118 1cin:A (2.1) BS02 MTS 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8142888 MOAD: Ki=1.88nM
    PDBbind: -logKd/Ki=8.73, Ki=1.88nM
    BindingDB: Ki=1.9nM
    119 1ckp:A (2.05) BS01 PVB 2.7.11.22 GO:0000082 ... P24941 9677190 BindingDB: IC50=6nM
    120 1cm0:A (2.3) BS01 COA 2.3.1.48
    2.3.1.57    		 GO:0004402 ... Q92831 10393169 BindingDB: IC50=41910nM
    121 1cm0:B (2.3) BS01 COA 2.3.1.48
    2.3.1.57    		 GO:0004402 ... Q92831 10393169 BindingDB: IC50=41910nM
    122 1cqe:A (3.1) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 8121489 BindingDB: IC50=150nM, Ki=1000nM
    123 1cqe:B (3.1) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 8121489 BindingDB: IC50=150nM, Ki=1000nM
    124 1cqp:A (2.6) BS02 803 ? N/A P20701 10493852 PDBbind: -logKd/Ki=5.62, IC50=2.4uM
    BindingDB: Kd=12900nM, IC50=2400nM
    125 1cqp:A (2.6) BS03 803 ? N/A P20701 10493852 PDBbind: -logKd/Ki=5.62, IC50=2.4uM
    BindingDB: Kd=12900nM, IC50=2400nM
    126 1cqp:B (2.6) BS01 803 ? N/A P20701 10493852 BindingDB: Kd=12900nM, IC50=2400nM
    127 1cqp:B (2.6) BS03 803 ? N/A P20701 10493852 BindingDB: Kd=12900nM, IC50=2400nM
    128 1ctr:A (2.45) BS05 TFP ? GO:0000086 ... P0DP23 7803388 PDBbind: -logKd/Ki=6.00, Kd=1uM
    BindingDB: Kd=1000nM
    129 1cva:A (2.25) BS02 AZI 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 8262987 BindingDB: Ki=1500000nM
    130 1cws:A (2.0) BS01 WO4 3.1.3.48 GO:0004725 ... P30305 10543950 BindingDB: IC50=30000nM
    131 1d0c:A (1.65) BS03 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    132 1d0c:A (1.65) BS04 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    133 1d0c:A (1.65) BS05 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    134 1d0c:B (1.65) BS02 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    135 1d0c:B (1.65) BS03 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    136 1d0c:B (1.65) BS05 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    137 1d0o:A (1.95) BS03 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    138 1d0o:A (1.95) BS04 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    139 1d0o:A (1.95) BS05 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    140 1d0o:B (1.95) BS02 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    141 1d0o:B (1.95) BS03 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    142 1d0o:B (1.95) BS05 INE 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=2000nM
    143 1d2s:A (1.55) BS02 DHT ? N/A P04278 10675319 PDBbind: -logKd/Ki=9.74, Kd=0.182nM
    BindingDB: IC50=3.8nM, Kd=0.182000nM
    144 1d3d:B (2.04) BS03 BZT 3.4.21.5 GO:0004252 ... P00734 10739244 MOAD: Ka=1240000000M^-1
    PDBbind: -logKd/Ki=9.09, Kd=0.81nM
    BindingDB: Ki=2.1nM
    145 1d3g:A (1.6) BS01 BRE 1.3.5.2 GO:0004151 ... Q02127 10673429 BindingDB: IC50=7nM
    146 1d3h:A (1.8) BS01 A26 1.3.5.2 GO:0004151 ... Q02127 10673429 BindingDB: IC50=300nM
    147 1d3t:B (3.0) BS03 BT1 3.4.21.5 GO:0004252 ... P00734 10739244 BindingDB: Ki=374nM
    148 1d7x:A (2.0) BS06 SPC 3.4.24.17 GO:0004222 ... P08254 10639284 PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=19nM
    149 1d7x:B (2.0) BS06 SPC 3.4.24.17 GO:0004222 ... P08254 10639284 PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=19nM
    150 1d8a:A (2.2) BS02 TCL 1.3.1.9 GO:0004318 ... P0AEK4 10201369 BindingDB: IC50=430nM
    151 1d8a:B (2.2) BS02 TCL 1.3.1.9 GO:0004318 ... P0AEK4 10201369 BindingDB: IC50=430nM
    152 1d8f:B (2.4) BS06 SPI 3.4.24.17 GO:0004222 ... P08254 10669564 MOAD: ic50=18nM
    PDBbind: -logKd/Ki=7.74, IC50=18nM
    BindingDB: IC50=18nM
    153 1d8m:B (2.44) BS06 BBH 3.4.24.17 GO:0004222 ... P08254 11327577 PDBbind: -logKd/Ki=8.51, IC50=3.1nM
    BindingDB: IC50=3.1nM
    154 1db1:A (1.8) BS01 VDX ? GO:0003677 ... P11473 10678179 MOAD: Kd=0.55nM
    PDBbind: -logKd/Ki=9.26, Kd=0.55nM
    BindingDB: EC50=10nM, IC50=1.1nM, Kd=0.065nM
    155 1db4:A (2.2) BS03 8IN 3.1.1.4 GO:0004623 ... P14555 7664108 PDBbind: -logKd/Ki=7.24, IC50=0.057uM
    BindingDB: IC50=57.0nM
    156 1db5:A (2.8) BS03 6IN 3.1.1.4 GO:0004623 ... P14555 7664108 PDBbind: -logKd/Ki=6.82, IC50=0.152uM
    BindingDB: IC50=69000nM
    157 1dcy:A (2.7) BS03 I3N 3.1.1.4 GO:0004623 ... P14555 7664108 BindingDB: IC50=13600nM
    158 1ddr:A (2.45) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 9260285 BindingDB: IC50=8.8nM, EC50=1nM
    159 1ddr:B (2.45) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 9260285 BindingDB: IC50=8.8nM, EC50=1nM
    160 1dds:A (2.2) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 9260285 BindingDB: IC50=8.8nM, EC50=1nM
    161 1dds:B (2.2) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 9260285 BindingDB: IC50=8.8nM, EC50=1nM
    162 1df1:A (2.35) BS04 ITU 1.14.13.39 GO:0004517 ... P29477 10562539 BindingDB: Ki=5.2nM
    163 1df1:B (2.35) BS03 ITU 1.14.13.39 GO:0004517 ... P29477 10562539 BindingDB: Ki=5.2nM
    164 1df7:A (1.7) BS02 MTX 1.5.1.3 GO:0004146 ... P9WNX1 10623528 MOAD: Ki=11nM
    BindingDB: IC50=8.8nM
    165 1df8:A (1.51) BS01 BTN ? GO:0009374 ... P22629 10850797 MOAD: Kd=0.2nM
    PDBbind: -logKd/Ki=9.70, Kd=0.20nM
    BindingDB: Kd=1.000000nM
    166 1df8:B (1.51) BS01 BTN ? GO:0009374 ... P22629 10850797 MOAD: Kd=0.2nM
    BindingDB: Kd=1.000000nM
    167 1dg5:A (2.0) BS02 TOP 1.5.1.3 GO:0004146 ... P9WNX1 10623528 MOAD: Ki=88uM
    BindingDB: IC50=88000nM
    168 1dgm:A (1.8) BS02 ADN 2.7.1.20 GO:0004001 ... Q9TVW2 10794412 PDBbind: -logKd/Ki=5.05, Ki=8.9uM
    BindingDB: Ki=8900nM
    169 1dhi:A (1.9) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 8265622 MOAD: Kd=55nM
    PDBbind: -logKd/Ki=7.26, Kd=55nM
    BindingDB: IC50=8.8nM, EC50=1nM
    170 1dhi:B (1.9) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 8265622 MOAD: Kd=55nM
    PDBbind: -logKd/Ki=7.26, Kd=55nM
    BindingDB: IC50=8.8nM, EC50=1nM
    171 1dhj:A (1.8) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 8265622 MOAD: Kd=281nM
    PDBbind: -logKd/Ki=6.55, Kd=281nM
    BindingDB: IC50=8.8nM, EC50=1nM
    172 1dhj:B (1.8) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 8265622 MOAD: Kd=281nM
    PDBbind: -logKd/Ki=6.55, Kd=281nM
    BindingDB: IC50=8.8nM, EC50=1nM
    173 1di8:A (2.2) BS01 DTQ 2.7.11.22 GO:0000082 ... P24941 10633045 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1uM
    BindingDB: IC50=1000nM
    174 1dib:A (2.7) BS02 L34 1.5.1.5
    3.5.4.9
    6.3.4.3    		 GO:0003824 ... P11586 10828945 BindingDB: IC50=96nM
    175 1dlr:A (2.3) BS02 MXA 1.5.1.3 GO:0000900 ... P00374 7890613 MOAD: Ki=16.4nM
    BindingDB: IC50=0.61nM, Ki=0.025nM
    176 1dls:A (2.3) BS02 MTX 1.5.1.3 GO:0000900 ... P00374 7890613 MOAD: Ki=10.9nM
    BindingDB: IC50=22nM, Kd=0.194984nM, Ki=4420nM, EC50=13.3nM
    177 1dmt:A (2.1) BS02 RDF 3.4.24.11 GO:0001786 ... P08473 10669592 PDBbind: -logKd/Ki=8.70, IC50=2nM
    BindingDB: IC50=30nM
    178 1dmy:A (2.45) BS02 AZM 4.2.1.1 GO:0004089 ... P23589 7479916 BindingDB: Ki=60nM
    179 1dmy:B (2.45) BS02 AZM 4.2.1.1 GO:0004089 ... P23589 7479916 BindingDB: Ki=60nM
    180 1dq8:A (2.1) BS02 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    181 1dq8:A (2.1) BS03 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    182 1dq8:B (2.1) BS01 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    183 1dq8:B (2.1) BS03 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    184 1dq8:C (2.1) BS02 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    185 1dq8:C (2.1) BS03 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    186 1dq8:D (2.1) BS02 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    187 1dq8:D (2.1) BS03 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    188 1dqa:A (2.0) BS02 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    189 1dqa:A (2.0) BS04 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    190 1dqa:B (2.0) BS01 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    191 1dqa:B (2.0) BS04 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    192 1dqa:C (2.0) BS03 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    193 1dqa:C (2.0) BS04 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    194 1dqa:D (2.0) BS02 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    195 1dqa:D (2.0) BS04 MAH 1.1.1.34 GO:0004420 ... P04035 10698924 BindingDB: Ki=23.5nM, IC50=4000nM
    196 1dqx:A (2.4) BS01 BMP 4.1.1.23 GO:0004590 ... P03962 10681417 MOAD: Ki=9pM
    PDBbind: -logKd/Ki=11.05, Ki=9pM
    BindingDB: Ki=0.0090nM
    197 1dqx:A (2.4) BS02 BMP 4.1.1.23 GO:0004590 ... P03962 10681417 MOAD: Ki=9pM
    PDBbind: -logKd/Ki=11.05, Ki=9pM
    BindingDB: Ki=0.0090nM
    198 1dqx:B (2.4) BS01 BMP 4.1.1.23 GO:0004590 ... P03962 10681417 MOAD: Ki=9pM
    PDBbind: -logKd/Ki=11.05, Ki=9pM
    BindingDB: Ki=0.0090nM
    199 1dqx:B (2.4) BS02 BMP 4.1.1.23 GO:0004590 ... P03962 10681417 MOAD: Ki=9pM
    PDBbind: -logKd/Ki=11.05, Ki=9pM
    BindingDB: Ki=0.0090nM
    200 1dqx:C (2.4) BS01 BMP 4.1.1.23 GO:0004590 ... P03962 10681417 MOAD: Ki=9pM
    BindingDB: Ki=0.0090nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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