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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL189568
Molecular formula	C23H29N3O4S2
IUPAC name	butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate
Molecular weight	475.622
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.3
Synonyms	477775-14-7 C-21 M024/C21 ZINC6467610 AKOS030231077 RC2V4W0EYC butyl 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate D0K2EX UNII-RC2V4W0EYC C21 N-Butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide BDBM50156173 SB18730 (1-((2''-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol Butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate GTPL6918 XTEOJPUYZWEXFI-UHFFFAOYSA-N Carbamic acid, [[3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)-2-thienyl]sulfon yl]-, butyl ester NCGC00386668-01 butyl (3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonylcarbamate compound 21 [PMID: 22802221] SCHEMBL557591 [ Show all ]
Inchi Key	XTEOJPUYZWEXFI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
PubChem CID	9804984
ChEMBL	CHEMBL189568
IUPHAR	6918
BindingDB	50156173
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
400309	Type-1 angiotensin II receptor	P30555	AGTR1	Sus scrofa (Pig)	359
400310	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
400311	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359
400308	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
555277	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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