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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL540553
Molecular formula	C38H46Cl3N3O6
IUPAC name	[(3R)-3-(3,4-dichlorophenyl)-3-[2-[4-(morpholine-4-carbonyl)-4-phenylpiperidin-1-yl]ethyl]pyrrolidin-1-yl]-(3,4,5-trimethoxyphenyl)methanone;hydrochloride
Molecular weight	747.151
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	None
Synonyms	SCHEMBL16353755
Inchi Key	UQQHUSGLRNUTHI-JFRIYMKVSA-N
Inchi ID	InChI=1S/C38H45Cl2N3O6.ClH/c1-46-32-23-27(24-33(47-2)34(32)48-3)35(44)43-18-12-37(26-43,29-9-10-30(39)31(40)25-29)11-15-41-16-13-38(14-17-41,28-7-5-4-6-8-28)36(45)42-19-21-49-22-20-42;/h4-10,23-25H,11-22,26H2,1-3H3;1H/t37-;/m0./s1
PubChem CID	9853505
ChEMBL	CHEMBL540553
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
343170	Substance-K receptor	P30549	Tacr2	Mus musculus (Mouse)	384
343169	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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