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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL313546
Molecular formula	C34H38Cl2FN3O5
IUPAC name	1-[2-[3-(3,4-dichlorophenyl)-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]ethyl]-4-(4-fluorophenyl)piperidine-4-carboxamide
Molecular weight	658.592
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50290310 SCHEMBL8351265 1-{2-[3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl}-4-(4-fluoro-phenyl)-piperidine-4-carboxylic acid amide
Inchi Key	SKQQTPWQQAVLTC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H38Cl2FN3O5/c1-43-28-18-22(19-29(44-2)30(28)45-3)31(41)40-17-11-33(21-40,24-6-9-26(35)27(36)20-24)10-14-39-15-12-34(13-16-39,32(38)42)23-4-7-25(37)8-5-23/h4-9,18-20H,10-17,21H2,1-3H3,(H2,38,42)
PubChem CID	44319222
ChEMBL	CHEMBL313546
IUPHAR	N/A
BindingDB	50290310
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
316716	Substance-K receptor	P30549	Tacr2	Mus musculus (Mouse)	384
316715	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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