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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	IIK7
Molecular formula	C22H24N2O2
IUPAC name	N-[2-(2-methoxy-6H-isoindolo[2,1-a]indol-11-yl)ethyl]butanamide
Molecular weight	348.446
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.7
Synonyms	N-[2-(2-methoxy-6H-isoindolo[2,3-a]indol-11-yl)ethyl]butanamide SR-01000075939-1 CHEMBL10009 IIK7, solid Lopac0_000701 NCGC00015557-03 EU-0100701 N-[2-(2-Methoxy-6H-isoindolo[2,1-a]indol-11-yl)-ethyl]-butyramide SCHEMBL19612546 CCG-204786 IIK-7 NCGC00015557-01 ZINC2510569 CTK8G0268 L000306 N-Butanoyl 2-(9-methoxy-6H-iso-indolo[2,1-a]indol-11-yl)-ethan-amine NCGC00094053-01 AC1N5IDZ GTPL1350 N-[2-(2-methoxy-6H-isoindolo[2,1-a]indol-11-yl)ethyl]butanamide SR-01000075939 NCGC00015557-02 D01SNS Lopac-I-5531 N-Butanoyl 2-(9-methoxy-6H-isoindolo[2,1-a]indol-11-yl)ethanamine NCGC00094053-02 BDBM50086013 I 5531 [ Show all ]
Inchi Key	RQYIUGOJQFWLAZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N2O2/c1-3-6-21(25)23-12-11-18-19-13-16(26-2)9-10-20(19)24-14-15-7-4-5-8-17(15)22(18)24/h4-5,7-10,13H,3,6,11-12,14H2,1-2H3,(H,23,25)
PubChem CID	4172142
ChEMBL	CHEMBL10009
IUPHAR	1350
BindingDB	50086013
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
302985	Melatonin receptor type 1A	P48039	MTNR1A	Homo sapiens (Human)	350
302984	Melatonin receptor type 1B	P49286	MTNR1B	Homo sapiens (Human)	362
554766	Melatonin receptor type 1B	Q8CIQ6	Mtnr1b	Mus musculus (Mouse)	364
302988	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
302986	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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