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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1672539
Molecular formula	C21H19Cl2N5
IUPAC name	3-chloro-5-(7-chloro-1-propylbenzimidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amine
Molecular weight	412.318
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50336921 SCHEMBL3633520 3-chloro-5-(7-chloro-1-propyl-1H-benzo[d]imidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amine
Inchi Key	RGKVPYQYBUAAEH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19Cl2N5/c1-3-9-28-19-16(22)5-4-6-18(19)27-21(28)14-10-17(23)20(25-11-14)26-15-8-7-13(2)24-12-15/h4-8,10-12H,3,9H2,1-2H3,(H,25,26)
PubChem CID	51033723
ChEMBL	CHEMBL1672539
IUPHAR	N/A
BindingDB	50336921
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
295459	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
295455	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
295456	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
295458	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
295457	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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